X-Ray Crystallography vs. NMR Spectroscopy

Skip to: Advantages of X-ray Crystallography vs. NMR Spectroscopy Disadvantages of X-ray Crystallography and NMR Spectroscopy X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy are two techniques used to study atomic structures. X-Ray crystallography scientific equipment used to resolve three-dimensional structure of biological molecules such as proteins and DNA – Image Credit: Gregory A. Pozhvanov […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. ARANESP® darbepoetin alfa Consumer Medicine Information (CMI) What is in this leaflet This leaflet answers some common questions about Aranesp (darbepoetin alfa). It does not contain all the available information. It does not take the place of talking to your doctor, nurse […]

What are Proteoforms (Protein Variation)?

Protein variation, which accounts for large amounts of the complexity in biological systems and our bodies, can come in many different forms. The different types of variation, namely variations in the molecular form of protein products, are united by the term proteoform (previously also known as protein forms, protein isoforms, protein species, and protein variants). […]

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes to the most reported therapy-resistant mechanism by which the cell-surface receptor HER3 counteracts HER2 targeting therapy in HER2-positive cancers. Removing […]

An Overview of Protein Quantification Methods

Elucidating information about proteins present in biological samples is vital for scientists working in the field of life sciences. Whilst qualitative data can tell us which proteins are present in a given sample, knowing the number of proteins in a sample can provide invaluable data and results. This article will provide a brief overview of […]

Researchers discover protein function that could improve chemotherapy in the future

Chemotherapy attacks all cells in our body and not just cancer cells, which is why patients undergoing the treatment often experience side effects such as physical weakness, hair loss and nausea. However, because cancer cells divide and spread faster than most normal cells, cancer cells are more sensitive to chemotherapy, which kills cells by inhibiting […]

Targeting T cell protein could prevent type 1 diabetes, study suggests

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes. The study, which will be published December 9 in the Journal of Experimental Medicine (JEM), reveals that inhibiting a protein called OCA-B protects mice from type 1 diabetes by limiting the activity of immune […]

AI system solves 50-year-old protein folding problem in hours

An artificial intelligence company that gained fame for designing computer systems that could beat humans at games has now made a huge advancement in biological science. The company, DeepMind, which is owned by the same parent company as Google, has created an AI system that can rapidly and accurately predict how proteins fold to get […]

The link between glaucoma, the immune system and protein tenascin-C

Researchers at Ruhr-Universität Bochum (RUB) have studied the role of the immune response in the development of glaucoma in mice. They showed that inflammatory processes are associated with the pathogenesis of the disease and that the extracellular matrix molecule tenascin-C plays a key role as a modulator of the immune response. Glaucoma is a common […]

Five ways to increase protein intake as we age

Protein is an essential part of a healthy diet. It helps us build and maintain strong muscles and bones, helps us better recover from illness and injury, and reduces likelihood of falls and fractures. But, as we age, many of us don’t get enough protein in our diet. This is partly because our appetites diminish […]