Insulin is one of the most well known hormones in the human body for its role in regulating blood glucose. While its absence or inaction causes diabetes (Type-I and Type-II), it is also associated with...

Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically. An...

Chronic psychosocial stress—which involves a pathway called the hypothalamic-pituitary-adrenal axis (HPA axis)—may contribute to the development of Alzheimer’s disease. A new review published...

The complex patterns of genetic ancestry uncovered from genomic data in health care systems can provide valuable insights into both genetic and environmental factors underlying many common and rare diseases—insights...

Ciliopathies are genetic disorders caused by defects in the structure and function of cilia, microtubule-based organelles present on the surface of almost every cell in the human body, which play crucial...

Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory...

Stem cells are considered one of the most promising tools in the field of regenerative medicine because they are a cell type that can give rise to all the cells in our bodies and that has the potential...

Cardiovascular disorders are leading causes of morbidity and death worldwide. Age-associated changes in arterial properties, such as endothelial dysfunction and structural alterations, are considered...

To replace aging and worn cells, the body primarily uses a process called mitosis, in which one cell divides into two. When a cell is ready to divide, it duplicates its DNA so a complete copy is available...