Patients treated with infliximab for inflammatory bowel disease (IBD) showed significantly reduced response to COVID-19 antibodies, compared with those treated with vedolizumab, according to data from nearly 7,000 patients. Although anti-tumor necrosis factor (anti-TNF) drugs are routinely used for patients with IBD, the impact of their immune-suppressing properties on protective immunity to COVID-19 is unknown, […]
NEW YORK (Reuters Health) – A subset of macrophages, PTGER4+ (EP4+), are the major drivers of epithelial regeneration after intestinal inflammation and are potential targets for inflammatory bowel disease (IBD) therapy, researchers say. “Dysfunctional resolution of intestinal inflammation and altered mucosal healing are essential features in the pathogenesis of IBD,” Dr. Gianluca Matteoli of KU […]
NEW YORK (Reuters Health) – Researchers have identified the process by which adherent-invasive Escherichia coli (AIEC) bacteria drive inflammation in Crohn’s disease. They found that AIEC, which colonize the intestinal mucosa by adhering to and invading intestinal epithelial cells, can produced a metabolite that interacts with the intestine’s immune cells to induce inflammation. “Our study […]
(HealthDay)—The risks for prematurity, small for gestational age, and cesarean section are increased in pregnancies among women with inflammatory bowel disease (IBD), according to a study published in the November issue of Alimentary Pharmacology & Therapeutics. Antoine Meyer, M.D., from the Assistance Publique-Hopitaux de Paris, and colleagues used data from the French national health system […]
(HealthDay)—Inflammatory bowel disease (IBD) patients do not have a higher risk for female genital tract malignancies, according to a study recently published in Digestive and Liver Disease. Maxine D. Rouvroye, from Vrije Universiteit Amsterdam, and colleagues investigated the risk for female genital tract malignancies, including vulvar and vaginal cancer, among patients with IBD. The analysis […]
Today, the American Gastroenterological Association (AGA) published new COVID-19 guidance for gastroenterologists treating patients with inflammatory bowel disease (IBD): AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary. While the COVID-19 pandemic is a global health emergency, patients with IBD have particular concerns for their risk for infection […]
How onions and old cheese could help inflammatory bowel disease: Scientists find diets rich in pre and probiotics ease gut cramps – but milk, pasta and rice will make them worse Researchers tested diet on 19 patients to see if would improve their gut health They found nearly two in three (61.3 per cent) reported […]
