Despite smoking's well-known role in causing lung cancer, a significant number of patients who develop lung tumors have never smoked. While scientists are still working to understand what spurs...

A study of microbial populations under a prolonged period of starvation by Indiana University professor Jay T. Lennon and his laboratory could help researchers answer questions pertaining to chronic...

In the first analysis of its kind, researchers at Columbia University Vagelos College of Physicians and Surgeons and several other institutions have linked distinct patterns of genetic mutations with...

A new class of drugs that inhibits a ‘master switch’ involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin’s lymphoma, has been discovered...

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice'...

In a multi-institutional study, researchers in the Developmental-Behavioral Pediatrics Research Network (DBPNet), led by Children's Hospital of Philadelphia (CHOP), have conducted the first and largest...

Around the world, 71 million people have been infected with the hepatitis C virus. The primary route of infection is through direct contact with another person’s blood. This means the virus can...

Unless you've studied chemistry in college, it's unlikely you've come across the name aziridine. An organic compound with the molecular formula, C2H4NH, aziridines are well-known among medicinal...

A new study, released on the bioRxiv* preprint server, shows that rapamycin, an immunosuppressive drug used in some cancers, and its analogs, may have an undesirable effect on viral entry into the host...

The lack of new or repurposed drugs to treat patients with severe or critical coronavirus disease 2019 (COVID-19) has been one of the biggest hurdles to reducing mortality rates in the ongoing pandemic...