Researchers find a protein involved in Huntington’s disease motor deficits

Huntington’s disease is caused by a mutation in the Huntingtin gen. Patients show involuntary movements, cognitive deficits and specific psychiatric disorders resulting from the degeneration and death of medium spiny striatal neurons. A study led by researchers of the Institute of Neurosciences of the UB (UBNeuro) describes the toxic role of the protein RTP801 in […]

Gut microbiome data may be helpful in routine screening of cardiovascular disease

Using artificial intelligence to analyze the bacteria in a person’s gut microbiome shows promise as a new screening method for cardiovascular disease (CVD), according to preliminary research to be presented Sept. 10-13, 2020, at the virtual American Heart Association’s Hypertension 2020 Scientific Sessions. The full study published simultaneously today in Hypertension, an American Heart Association […]

Study targets gene associated with Alzheimer’s disease

Researchers at the University of Alabama at Birmingham are on the track of a gene that might play a role in the development of Alzheimer’s disease. The research team is studying a gene called BIN1, which was first linked to Alzheimer’s disease in 2009. In a paper recently published online in eLife, the team shows […]

Psychological disease avoidance linked to preventative behavior

Creeped out by cooties? Grossed out by germs? Squeamish about sickness? If so, then you might also find yourself engaging in more preventative health behaviors, like frequent handwashing and disinfecting your living environment, during the ongoing coronavirus pandemic. More than other factors, strong feelings of germ aversion and pathogen disgust are significantly associated with concern […]

Unique protein structures could hold the key to Parkinson’s disease

Scientists at the University Bath have discovered a series of protein structures that are thought to be highly relevant to the onset of Parkinson’s disease. It is hoped that further analysis of these structures will open up a new avenue for potential treatment for a disease that is the fastest growing neurological condition in the […]

Antibiotics use early in life increases risk of inflammatory bowel disease later in life

Even short, single antibiotic courses given to young animals can predispose them to inflammatory bowel disease (IBD) when they are older, according to Rutgers researchers. The study, published in Genome Medicine, provides further evidence supporting the idea that the use of antibiotics in children under 1 year old disrupts the intestinal microbiota—the trillions of beneficial […]

Hawaiʻi youth have high rates of chronic disease

Chronic diseases typically associated with middle age and older adulthood are common in young people needing hospital care in Hawaiʻi, according to public health researchers from the University of Hawaiʻi at Mānoa. More than a quarter of hospitalized youth and 12 percent of youth who visited an emergency department had at least one chronic condition […]

Dual role discovered for molecule involved in autoimmune eye disease

The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A’s pro-inflammatory activity, according to a study by National Eye Institute (NEI) researchers. In models of autoimmune diseases of the eye and brain, blocking IL-17A increased the presence of other inflammatory molecules produced by Th17 cells, immune cells that produce IL-17A and are […]