Sufferers of Parkinson’s disease have clumps of α-synuclein (alpha-synuclein), sometimes known as the “Parkinson’s protein,” found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a method developed at Chalmers University of Technology, Sweden, reveals how the composition of cell membranes seems to be a decisive factor for how small quantities […]
The key to swift treatments to cure the pain of rheumatoid arthritis has been found in the joints of people with the condition who are in long-term remission. The study—published today in Nature Medicine and led by the University of Glasgow in collaboration with Fondazione A.Gemelli IRCCS in Italy and the Versus Arthritis funded Research […]
A new, hair-sprouting dollop of human skin created in the lab might one day help prevent hair loss. Organoids are small, lab-grown cell groupings are designed to model real-world organs -in this case, skin. A paper published in Nature describes the hairy creation as the first hair-baring human skin organoid made with pluripotent stem cells, […]
Lung cancers account for approximately 25 percent of all cancer deaths. Even among those who do not smoke, 1 in 15 men and 1 in 17 women are expected to develop lung cancer in their lifetime, according to the American Cancer Society. Lung cancer has confounded scientists who strive to develop better therapies for this […]
To replace aging and worn cells, the body primarily uses a process called mitosis, in which one cell divides into two. When a cell is ready to divide, it duplicates its DNA so a complete copy is available for each of the daughter cells. In this process, the DNA pieces, or chromosomes, must be precisely […]
Preeclampsia is the leading cause of death and disability, for both mothers and babies, killing approximately 76,000 mothers and 500,000 babies globally every year. Despite this, the only cure at present is to deliver the placenta and the baby, with the potential for long term complications. In recent years stem cell therapies have been investigated […]
Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests. The findings, published in a recent issue of Nature Immunology, could eventually lead to new ways to augment existing treatments to fight this […]
In a study published this week in Science, Université de Montreal researchers report key structural and biochemical differences among a class of anti-cancer drugs known as PARP inhibitors. These distinguishing differences were linked to differing capacities of PARP inhibitors to kill cancer cells. The research resolves a long-standing and perplexing quandary over differences between the […]
Researchers at Karolinska Institutet in Sweden and the University of Milan in Italy have identified a gene in human neurons that protects against the degeneration of motor neurons in the deadly diseases ALS and SMA. Gene therapy in animal models of these diseases was shown to protect against cell death and increase life expectancy. The […]
