Immunotherapy is beneficial in gastric and oesophageal cancers, studies show

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and oesophageal cancers who currently have poor survival. Immune therapy would be a big change in treatment, since immune checkpoint inhibitors are not yet approved for early therapy in Western countries. Three studies provide evidence, based on different patient […]

Precision medicine identifies key recurring mutation in head and neck cancers

Head and neck cancer is one of the leading causes of cancer-related deaths worldwide, and squamous cell carcinomas (HNSCC) account for the majority of these cases. In a new study, based on preclinical research and published July 29, 2020 in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research, researchers at University […]

Aspirin linked to reduction in risk of several cancers of the digestive tract

Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers. The largest and most comprehensive analysis to date of the link between aspirin and digestive tract cancers, published in the leading cancer journal Annals of […]

Manipulating cell death signaling after radiation could offer a new way to treat cancers

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests. The findings, published in a recent issue of Nature Immunology, could eventually lead to new ways to augment existing treatments to fight this […]

‘Genetic rewiring’ drives cancer’s drug resistance

A tiny molecule of RNA—known as ‘micro RNA’ – plays a key role in ‘rewiring’ cancer cells so they can resist the effects of chemotherapy, a new study reveals. The discovery opens up the possibility of creating new cancer drugs that target this micro RNA molecule, rather than more conventional treatments that block the action […]