Scientists at Stanford University and the University of North Carolina at Chapel Hill have created a 3D-printed vaccine patch that provides greater protection than a typical vaccine shot. The trick is applying the vaccine patch directly to the skin, which is full of immune cells that vaccines target. The resulting immune response from the vaccine […]
Malaria remains a deadly disease that affects people worldwide, particularly in Africa. Caused by a parasite that can enter the human bloodstream via mosquito bite, the parasites can then infect and reproduce within the person's liver. Significant effort has been made to develop an anti-malaria vaccine; unfortunately, previous vaccine candidates have had low-to-modest efficacies. Now, […]
Breathe in, breathe out. That’s how easy it is for SARS-CoV-2, the virus that causes COVID-19, to enter your nose. And though remarkable progress has been made in developing intramuscular vaccines against SARS-CoV- 2, such as the readily available Pfizer, Moderna and Johnson & Johnson vaccines, nothing yet—like a nasal vaccine—has been approved to provide […]
A century-old tuberculosis vaccine could help reduce the incidence of eczema in high-risk infants due to its beneficial off-target effects, according to a new MCRI-led allergy study. Bacille Calmette-Guérin (BCG), a vaccine used in Australia until the 1980s to prevent tuberculosis, had been tested in a trial to see if it can reduce the rate […]
The allocation of COVID-19 vaccine between countries has thus far tended toward vaccine nationalism, wherein countries stockpile vaccines to prioritize access for their citizenry over equitable vaccine sharing. The extent of vaccine nationalism, however, may strongly impact global trajectories of COVID-19 case numbers and increase the potential emergence of novel variants, according to a Princeton […]
The US Food and Drug Administration (FDA) has approved Pfizer’s TicoVac vaccine for the treatment of tick-borne encephalitis (TBE). The vaccine is approved outside of United States, and more than 170 million doses have been administered since 1976. The World Health Organization (WHO) recommends vaccination for everyone in areas where the annual incidence of clinical disease […]
This is the first tranche of the 100 million vaccines the Prime Minister pledged the UK would share within the next year at last month's G7 in Cornwall, 80 million of which will go to COVAX, a scheme that ensures equitable, global access to Covid-19 vaccines. The consignment arrived in Malawi on Saturday, 14 August […]
Scientists at Children's Hospital of Philadelphia (CHOP) have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi). Working in a mouse model, the investigators found that administering two bacterial adhesive proteins that play a key role in helping the bacteria to latch on to respiratory cells and initiate […]
Researchers in Austria have conducted a study showing that individuals previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit a significantly more pronounced antibody response to one dose of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine than previously uninfected individuals. The team from the Medical University of Vienna says that an astonishing 20- to […]
The Medicines Patent Pool (MPP) and the World Health Organization (WHO), Afrigen Biologics (PTY) Limited, the Biologicals and Vaccines Institute of Southern Africa (Biovac), the South African Medical Research Council (SAMRC) and Africa Centres for Disease Control and Prevention (Africa CDC) have signed a letter of intent to address the global imbalance of manufacturing capacity […]
