Formula milk trials are not reliable, warn experts

Formula milk trials have a high risk of bias, authors almost always report favorable conclusions, transparency is lacking, and findings are selectively reported, finds a review of evidence from recently published trials in The BMJ today. The researchers say their findings “support the need for a substantial change in the conduct and reporting of formula […]

Most trials in primary care stand the test of time

According to a new paper in Family Practice, published by Oxford University Press, while medical practice is often undermined by subsequent investigation, randomized trials relevant to primary care generally hold up over time. Medical reversal describes a problem whereby new research leads doctors to stop using a popular medication, procedure or diagnostic test that had […]

AstraZeneca hails US trials as EU rows with UK over supplies

Pharmaceutical giant AstraZeneca said Monday that trials showed its COVID-19 vaccine was 100 percent effective in preventing severe disease, as a row simmered between Britain and the EU over much-needed supplies of the jab. The AstraZeneca shot is cheaper and easier to store than many of its rivals, several countries in Europe and other parts […]

Clinical trials in the era of digital engagement: A SWOG call to action

Social media is an integral part of medicine, and an increasingly important conduit for sharing information about clinical trials. In an article in JCO Clinical Cancer Informatics, researchers from SWOG Cancer Research Network pose provocative questions aimed at sparking discussion and creating consensus on how cancer clinical trial stakeholders can best interact on social platforms. […]

On the frontlines: How clinical trials are key to fighting viruses

In March, someone in Seattle became the first person in the United States to take an experimental dose of a potential vaccine for the novel coronavirus, COVID-19. Doctors injected 45 healthy people as part of a clinical trial they hope will protect people from a virus that has killed tens of thousands and upended normalcy […]