Volunteer in AstraZeneca coronavirus clinical trial dies, report says

AstraZeneca, Oxford resume stage-three U.K. trials of potential coronavirus vaccine Professor of surgery at John Hopkins School of Medicine Dr. Marty Makary weighs in on ‘Fox Report.’ A volunteer involved in AstraZeneca and Oxford University’s coronavirus vaccine trial has died, Brazilian health authority Anvisa announced on Wednesday, according to Reuters. An investigation into the death […]

Genomic study of 6000 NCI-MATCH cancer patients leads to new clinical trial benchmarks

Five years ago, the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and National Cancer Institute (NCI), part of the National Institutes of Health, jointly launched a very different kind of cancer study. NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131), the largest precision medicine cancer trial to date, sought to match genetic abnormalities driving patients’ tumors with […]

Fred Hutch-led clinical trial shows new smartphone app helps smokers quit

Scientists at Fred Hutchinson Cancer Research Center believe they’ve found a better of use of mobile technology to help adult cigarette smokers quit. In a large clinical trial published in JAMA Internal Medicine, a team led by Dr. Jonathan Bricker, a professor in Fred Hutch’s Public Health Sciences Division, tested the efficacy of the new […]

Investigational ALS drug generates promising clinical trial results

An experimental medication slows the progression of the neurodegenerative disease called Amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, according to recently released results from a clinical trial run by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH) and Amylyx Pharmaceuticals, Inc., the company that manufactures the […]

Pfizer’s COVID vaccine shows ‘robust’ results in early trial

(HealthDay)—A vaccine based on cutting-edge RNA gene technology showed promising potency against the new coronavirus in an early trial, scientists report. The vaccine candidate—for now just called BNT162b1—”elicited a robust immune response in participants, which increased with dose level and with a second dose,” according to a news release from the journal Nature, which published […]

US announces clinical trial of antibody treatment for COVID-19

The US has begun late stage clinical trials into a drug formulated to fight COVID-19, officials said Tuesday. The medicine is an antibody against the new coronavirus called LY-CoV555, which was identified in the blood sample of a recovered patient by Canada’s Abcellera Biologics. It was then developed synthetically for mass production by US-based Lilly […]

In early trial, an ancient drug shows promise against severe COVID-19

There’s new evidence that a 2,000-year-old medicine might offer hope against a modern scourge: COVID-19. The medication, called colchicine, is an anti-inflammatory taken as a pill. It’s long been prescribed for gout, a form of arthritis, and its history goes back centuries. The drug was first sourced from the autumn crocus flower. Doctors also sometimes […]

Researchers design clinical trial on use of exercise for severe liver disease

A team of Penn State researchers developed a first-of-its-kind clinical trial to test the use of exercise as a treatment for patients with a severe form of nonalcoholic fatty liver disease. Nonalcoholic fatty liver disease is the leading cause of chronic liver disease in the United States. People with this disease have an extra fat […]

New coronavirus vaccine trial starts this week in the UK

A coronavirus vaccine candidate will be tested in a clinical trial in the United Kingdom  starting this week. The vaccine combines a weakened version of a common cold virus with genes coding for the coronavirus’ lethal weapons: its spikes. The vaccine will be administered to people starting on Thursday (April 22), British Health Minister Matt […]