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A phase 2 clinical trial whose results were released today in Stem Cells Translational Medicine might point to a way to overcome bronchopulmonary dysplasia (BPD), a major cause of death in preterm infants. The study, conducted by researchers at Samsung Medical Center, Sungkyunkwan University and Asan Medical Center Children’s Hospital in Seoul, evaluates the effectiveness […]
A hydrogel developed at Hokkaido University successfully reverted cancer cells back to cancer stem cells within 24 hours in six different human cancer types. This could lead to the development of anti-cancer stem cell drugs and personalized medicines. Cancer is the leading cause of death in developed countries, and more than 8.6 million people die […]
Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery. For more than half of the patients, substantial improvements in key functions—such as ability to walk, […]
Leukemia is caused by leukemic stem cells which are resistant to most known therapies. Relapses are also due to this resistance. Leukemic stem cells arise from normal blood-forming (hematopoietic) stem cells. Because they are closely related, leukemic and hematopoietic stem cells share many of the same signaling pathways. If the proliferation of leukemic stem cells […]
Nonalcoholic fatty liver disease (NAFLD) is a widespread condition in the Western World. Around 30% of the population have lipid droplets stored in their liver which diminish its function in the long term. Main causes for NAFLD are our high-caloric diet in combination with a sedentary lifestyle. Hitherto, researchers have not fully understood the cause […]
(HealthDay)—Among older patients with myelodysplastic syndrome (MDS), survival rates are better for those undergoing allogeneic hematopoietic cell transplantation (HCT), according to a study presented at the annual meeting of the American Society of Hematology, held virtually from Dec. 5 to 8. Ryotaro Nakamura, M.D., from the City of Hope in Duarte, California, and colleagues conducted […]
Stem cells are considered one of the most promising tools in the field of regenerative medicine because they are a cell type that can give rise to all the cells in our bodies and that has the potential to be used to treat tissue loss due to damage or disease. Stem cells that are similar […]
Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat and muscle cells. But it’s their ability to stimulate the repair of damaged tissue that has captured the interest of researchers worldwide, with MSCs demonstrating therapeutic effects in the treatment of conditions such as heart disease, […]
Preeclampsia is the leading cause of death and disability, for both mothers and babies, killing approximately 76,000 mothers and 500,000 babies globally every year. Despite this, the only cure at present is to deliver the placenta and the baby, with the potential for long term complications. In recent years stem cell therapies have been investigated […]
