A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method– "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq — that can help discover numerous modified small RNAs that were previously undetectable. RNA plays a central role in decoding the genetic information in DNA […]
Cell Migration Assays from Platypus Technologies utilize exclusion-zone technology, ensuring that results are high quality and ideal for publication. Researchers in both pharmaceutical companies and academia will benefit from the use of robust, powerful Cell Migration Assays by Platypus Technologies, particularly in studies looking to advance cancer research, drug discovery, or wound healing. Cell Migration […]
COVID-19 has changed the way many people live and work. It has also had an impact on the ways many scientists collaborate and carry out their research—and how they release their findings. The need for speed in the fast-changing research landscape of the pandemic put pressure on biomedical researchers to share their work as fast […]
New research led by investigators at Massachusetts General Hospital (MGH) provides insights on why people with red hair exhibit altered sensitivity to certain kinds of pain. The findings are published in Science Advances. In people with red hair (as in numerous other species of animals with red fur), the pigment-producing cells of the skin–called melanocytes–contain […]
An international survey that included 600 smokers in the UK has found that cessation messaging focused on easing the burden on our health system is most effective in encouraging people to quit. The research, which was conducted in April-May 2020, randomly assigned participants to view one of four quit smoking messages, two of which explicitly […]
Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients. The discovery points the way to a search for novel treatments for the disease as well as […]
Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp containing nerves and blood vessels. We found that odontoblasts, which support the shape of the tooth, are also responsible for sensing cold. This research […]
A decline in cognitive functions – such as memory, attention and decision-making – is connected to the tightest restrictions in Scotland's COVID-19 lockdown, a new peer-reviewed study has found. The research, led by Dr Joanne Ingram from the University of the West of Scotland (UWS), in partnership with Glasgow Caledonian University (GCU), has concluded that […]
A research team at the Greenwood Genetic Center (GGC) has identified the mechanism that causes movement disorders in patients with mutations in the NUS1 gene. Using both cellular and model organism studies, cholesterol accumulation was found to contribute to the symptoms of seizures, ataxia, and movement abnormalities. This breakthrough study on NUS1, a gene that […]
Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig's Disease (ALS). Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of […]
