Lung cancer is the most lethal cancer in the world. Surgical lobectomy combined with systematic lymph node dissection (LND) is the current preferred treatment for patients with lung cancer. Accurate prediction of lymph node (LN) metastasis status before operation will avoid invalid LNDs, and thus reduce the risk of recurrence and complications. A research team […]
University of Minnesota researchers have developed a novel virus-like particle vaccine against COVID-19. Having been successfully tested in animals, the novel vaccine—created as part of a study whose findings were recently published in the scientific journal PLOS Pathogens—offers a new approach in the global battle against COVID-19 and its emerging variants. The researchers combined the […]
A new class of drugs that inhibits a ‘master switch’ involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin’s lymphoma, has been discovered by researchers at Mount Sinai. In a study in Clinical Cancer Research published in June, the team reported that the drugs, known as small-molecule […]
A novel form of macrophage-based immunotherapy is effective at treating a broad spectrum of cancers, including those at advanced stages, according to a groundbreaking study led by Georgia State immunology professor Yuan Liu. Liu’s treatment works by leveraging macrophages, specialized white blood cells involved in the detection and elimination of cancer cells and other pathogens. […]
Type I diabetes mellitus (T1D) is an autoimmune disorder leading to permanent loss of insulin-producing beta-cells in the pancreas. In a new study, researchers from the University of Tokyo developed a novel device for the long-term transplantation of iPSC-derived human pancreatic beta-cells. T1D develops when autoimmune antibodies destroy pancreatic beta-cells that are responsible for the […]
As reported in Nature Communications, researchers from Cleveland Clinic’s Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease. The team used the model to identify a promising target that could be inhibited to slow disease progression.Ulcerative colitis is […]
Soon after rapamycin, the first mTOR inhibitor, emerged in 1990s as a potential treatment against unwanted cell proliferation, many cancer experts had hoped emerging drugs targeting mTOR would become a breakthrough targeted therapy for children and adults suffering relapses of acute myeloid leukemia (AML) and other cancers where mTOR activity is abnormally high. However, numerous […]
Researchers at Helmholtz Zentrum München together with LMU University Eye Hospital Munich and the Technical University of Munich (TUM) created a novel deep learning method that makes automated screenings for eye diseases such as diabetic retinopathy more efficient. Reducing the amount of expensive annotated image data that is required for the training of the algorithm, […]
Cancer diagnosis requires a lengthy process of multiple analyses of tissue biopsies, impeding the quick and early detection of cancers. In a new study, researchers from Osaka University developed a novel imaging system that uses near-infrared light to be less invasive and more time efficient than the conventional approach. Histopathological analysis, or the investigation of […]
Researchers at the Center for Cognition and Sociality, within the Institute for Basic Science (IBS), Gwangju Institute of Science and Technology (GIST), and Korea Institute of Science and Technology (KIST) have discovered a new mechanism to explain the effects of subcortical strokes and a new possible therapeutic approach. Every year, 15 million people worldwide suffer […]
