A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell. The target, known as ZMYND8, isn’t a mutated gene, rather an epigenetic regulatory […]
Bile duct cancer is a rare but aggressive form of cancer, affecting just over 2,000 people in the UK every year. However, incidences of bile cancer are steadily increasing every year—with some estimating it could one day be as common as breast cancer. Also known as cholangiocarcinoma, bile duct cancer happens when the lining cells […]
Help wanted ad: The Central Intelligence Agency (CIA) is looking for primary care specialists and psychiatrists “to keep our Nation safe,” a CIA online job ad says. The recent death of famed CIA profiler Jerrold M. Post, MD, psychiatrist, triggered renewed discussion of physician involvement in medical intelligence work, including controversy over its ethics and medical […]
(HealthDay)—Angie Gaytan never cared much for beets, but beets sure do love her—doctors say that veggie shakes, fruits, beet juice and other healthy foods likely helped the 16-year-old defeat her life-threatening leukemia. Such a healthy diet helped more than Angie: A new study found that adopting a low-fat, low-sugar diet appeared to boost the effectiveness […]
WEDNESDAY, Oct. 21, 2020 — A combination of two “targeted” therapies can beat back a rare form of blood cancer — without the toxic effects of chemotherapy, a new study has found. In a trial of 63 patients, researchers found that the drug regimen frequently wiped out all signs of the cancer — a subtype […]
Researchers at Mount Sinai have discovered that human acute myeloid leukemia (AML) stem cells are dependent on a transcription factor known as RUNX1, potentially providing a new therapeutic target to achieve lasting remissions or even cures for a disease in which medical advances have been limited. In a study published in June in Cell Reports, […]
