The human brain is less accessible than other organs because it is covered by a thick, hard skull. As a result, researchers have been limited to low-resolution imaging or analysis of brain signals measured outside the skull. This has proved to be a major hindrance in brain research, including research on developmental stages, causes of […]
More evidence is urgently needed on opioid use in Black communities
Although the prevalence of opioid use among Black people is comparatively low, the rate of opioid deaths has increased the sharpest and fastest among that population in recent years, according to an article in the March/April issue of Harvard Review of Psychiatry. The review by Ayana Jordan, MD, Ph.D., of Yale University School of Medicine […]
Researchers discover ‘gene cooperation’ in cancer growth and can target treatments to stop it
Cooperation is generally a good thing—working together to reach a goal. But in the case of cancer, it can be detrimental. University of Cincinnati researchers have discovered that cooperation between two key genes drive cancer growth, spread and treatment resistance in one particularly aggressive type of breast cancer. The good news is, though, with this […]
Mix of treatments could be way to restore hand function in thumb-base osteoarthritis
The base of our thumb may be just a small part of our hand, but we rely on it more than we think. Arthritis in that area can have large consequences, often making simple actions such as picking up an object or opening a door an obstacle. Osteoarthritis, which is a type of arthritis, is […]
Immune cells in cerebrospinal fluid predict response to immunotherapy
Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies. Immune checkpoint inhibitors including anti-PD1, anti-PD-L1, and […]
Huntington’s disease driven by slowed protein-building machinery in cells
In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington’s disease, raising high hopes for a quick cure. Yet today, there’s still no approved treatment. One difficulty has been a limited understanding of how the mutant huntingtin protein sets off brain cell death, says neuroscientist Srinivasa Subramaniam, Ph.D., of Scripps Research, Florida. In […]
CVD risk factors tied to cognitive impairment in schizophrenia
(HealthDay)—Cardiovascular risk factors are associated with cognitive impairment among individuals with schizophrenia, according to a review and meta-analysis published online March 3 in JAMA Psychiatry. Katsuhiko Hagi, Ph.D., from Sumitomo Dainippon Pharma in Tokyo, and colleagues conducted a systematic review and meta-analysis to examine the association between risk factors for cardiovascular disease (CVD) and cognition […]
Study reveals impact of lockdown on violence in a UK capital city
The first UK COVID-19 lockdown saw a “rapid and sustained” fall in violence outside the home in the Welsh capital city, a new study led by Cardiff University has shown. Researchers from Cardiff University’s Crime and Security Research Institute (CSRI) and the US Centers for Disease Control and Prevention studied data from Cardiff’s sole emergency […]
Around 1 in 6 sports bettors started a new form of gambling during the initial COVID-19 lockdown
Around one in six sports bettors started a new form of gambling during the initial COVID-19 lockdown, and one in three placed bets more frequently, according to a new study. Experts from the Universities of Glasgow and Stirling explored gambling behaviors of those who regularly bet on sports before and during the first U.K. lockdown […]
States Aim to Chip Away at Abortion Rights With Supreme Court in Mind
When Rep. Lola Sheldon-Galloway introduced a bill in the Montana House two years ago that would have prohibited abortions after 20 weeks of pregnancy, the Republican legislator knew it was unlikely to survive the veto pen of the Democratic governor. Sure enough, then-Gov. Steve Bullock vetoed that bill and two other anti-abortion measures passed by […]