Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder, causes fluid-filled cysts to develop on the kidneys, which can impair their function. As part of the growth of cysts, the kidneys develop inflammation and fibrosis, or scarring. The disease is most often caused by a mutation in one of two genes, PKD1 or PKD2, which […]
Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools […]
Hispanic people with a high percentage of American Indigenous ancestry are at increased risk of a nutritional deficiency that could affect their heart health and contribute to harmful inflammation, new research suggests. Salmon are rich in omega-3 fatty acids. A new study suggests that Hispanic Americans may be at elevated risk of omega-3 deficiency if […]
Alex stood in front of a mirror observing himself. "What color?" he inquired of no one in particular. He stared at his reflection a little longer before repeating the question: "What color?" Alex was a gray parrot purchased from a pet shop by psychologist Irene Pepperberg in 1977. To date, Alex is perhaps the only […]
Historically, most large-scale immunogenomic studies—those exploring the association between genes and disease—were conducted with a bias toward individuals of European ancestry. Corey T. Watson, Ph.D., assistant professor in the University of Louisville Department of Biochemistry and Molecular Genetics, is leading a call to actively diversify the genetic resources he and fellow immunogenomics researchers use in […]
University of Maryland School of Medicine (UMSOM) researchers identified a new gene that may be linked to certain neurodevelopmental disorders and intellectual disabilities. The researchers believe that finding genes involved in certain types of developmental disorders, provide an important first step in determining the cause of these disorders and ultimately in developing potential therapies for […]
Researchers at the University of California San Diego have laid the groundwork for a potential new type of gene therapy using novel CRISPR-based techniques. Working in fruit flies and human cells, research led by UC San Diego Postdoctoral Scholar Zhiqian Li in Division of Biological Sciences Professor Ethan Bier's laboratory demonstrates that new DNA repair […]
Targeting a pathway that is essential for the survival of certain types of acute myeloid leukaemia could provide a new therapy avenue for patients, the latest research has found. Researchers from the Wellcome Sanger Institute found that a specific genetic mutation, which is linked with poor prognosis in blood cancer, is involved in the development […]
A new study with the University of Copenhagen represented indicates that the coronavirus variant called P.1, which originated in Brazil, could pose a bigger threat than previously assumed. The researchers conclude that it is likely that P.1 is more transmissible than other strains of SARS-Cov2 and that might be able to evade immunity gained from […]
The complex patterns of genetic ancestry uncovered from genomic data in health care systems can provide valuable insights into both genetic and environmental factors underlying many common and rare diseases—insights that are far more targeted and specific than those derived from traditional ethnic or racial labels like Hispanic or Black, according to a team of […]
