New research published in the bioRxiv* preprint server suggests a small cationic peptide known as crotamine may inhibit the replication and transcription of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Crotamine in the D-enantiomer form successfully inhibited SARS-CoV-2 replication by targeting the C30 Endopeptidase (3CLpro protease). Study: Design of D-amino acids SARS-CoV-2 Main protease inhibitors […]

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged in late 2019 in Wuhan, China. The virus rapidly spread worldwide, causing millions of morbidity and mortality cases, known as the coronavirus disease 2019 (COVID-19) pandemic. To combat the spread and effects on human health, scientists from various fields came together in a focused effort to […]

Lupus can cause genetic changes that support type I interferon (IFN) pathway activation. But the reason behind people continue to have a high frequency of lupus-associated risk alleles in the immune system remains poorly understood. Timothy B. Niewold of the Colton Center for Autoimmunity at the NYU Grossman School of Medicine and colleagues hypothesized that […]

In the face of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants such as Delta, reasonable concerns have been raised over how COVID-19 vaccines are affected. But new research finds people continue to have high vaccine effectiveness until around 6 months after being vaccinated. More than 4.9 million individuals were assessed for eligibility between […]

The coronavirus disease 2019 (COVID-19) pandemic has been a heavy blow to the world's health and wealth but is generally thought to have spared children. It is necessary to take a fresh look at it, however, in light of the fact that pediatric vaccination with COVID-19 vaccines is still not generally approved while more and […]

Even with the rapid production and distribution of safe and effective coronavirus disease 2019 (COVID-19) vaccines, their availability in low-resource settings is an issue due to production, affordability, and allocation challenges. Therefore, it is important to identify inexpensive, effective, and widely available COVID-19 therapies. Study: Effect of early treatment with fluvoxamine on risk of emergency […]

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a ribonucleic acid (RNA) virus that causes the coronavirus disease 2019 (COVID-19). RNA viruses are prone to high rates of mutation. In fact, it has been reported that in SARS-CoV-2, 10−3 substitutions occur on each site of the virus every year. Study: Mutational hotspot in the SARS-CoV-2 […]

The United Kingdom began the widespread distribution of coronavirus disease 2019 (COVID-19) vaccines in early December 2020. By September 27, 2021, 89.6% of the adult population in the U.K. had received at least one dose of the vaccine. High vaccination rates have been associated with reduced hospital admissions, thereby providing healthcare systems some relief from […]

The rapid spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has resulted in the coronavirus disease 2019 (COVID-19) pandemic. To contain this pandemic, scientists have developed several vaccines, and many of those have received emergency use authorization (EUA) from global regulatory bodies. Subsequently, vaccination programs have commenced in many countries. Study: A cohort of 222 […]

There was a difference in disease burden observed during the initial waves of the COVID-19 pandemic due to different infection rates influenced by factors including the type of occupation, ability to shelter in place, usage of sick leave, access to testing, housing status, and crowded conditions in the neighborhood. Comorbidities like diabetes and heart disease […]