When a new drug is being developed, the first question is, “Does it work?” The second question is, “Does it do harm?” No matter how effective a therapy is, if it harms the patient...

A hydrogel developed at Hokkaido University successfully reverted cancer cells back to cancer stem cells within 24 hours in six different human cancer types. This could lead to the development of anti-cancer...

Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome stability at chromosome ends and is...

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate...

In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington’s disease, raising high hopes for a quick cure. Yet today, there’s still no approved treatment. One difficulty...

Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report...

Leukemia is caused by leukemic stem cells which are resistant to most known therapies. Relapses are also due to this resistance. Leukemic stem cells arise from normal blood-forming (hematopoietic) stem...

Origin of cell lines – a woman named Henrietta Lacks Image Credit: Koliadzynska Iryna/Shutterstock.com Today, cell lines derived from animals including humans are grown and used for research in...

How does the “body” take shape? The body of animals is highly complex, containing distinct regions that carry out specific functions. As the body forms during embryogenesis, three germ layers are...

A tumor is an abnormal growth of cells within the body, usually facilitated by a lack of apoptosis (natural cell death), therefore allowing for uncontrolled growth of unwanted or damaged cells. Tumors...