Covid can infect cells of inner ear and may lead to hearing loss

COVID-19 can infect cells of the inner ear – and potentially lead to hearing loss and tinnitus, study finds Researchers creates models of different types of inner ear cells, including hair cells, supporting cells, nerve fibers and Schwann cell These models were then compared with 10 Covid patients who reported a number of ear-related symptoms […]

Key immune cells maintain healthy gut bacteria to protect against colorectal cancer

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialog between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type […]

Distress signal from fat cells prompts heart to shore up defenses against consequences of obesity

A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests. The finding, published online in Cell Metabolism, could help explain the “obesity paradox,” a phenomenon in which obese individuals have better short- and medium-term cardiovascular disease prognoses compared with those who […]

Brain cells in Alzheimers patients consume resources essential to neurotransmission

Alzheimer’s disease (AD), the most common type of dementia, causes the death of neurons and leads to shrinking of the brain. Patients with AD will eventually experience gradual deterioration in memory, thinking, behavior and the ability to perform everyday activities. Yet, scientists do not fully understand what causes this disease. A recent study conducted by […]

Zombie cells hold clues to spinal cord injury repair

Mammals have a poor ability to recover after a spinal cord injury, which can result in paralysis. A main reason for this is the formation of a complex scar associated with chronic inflammation that produces a cellular microenvironment blocking tissue repair. Now, a research team led by Leonor Saude, group leader at Instituto de Medicina […]

Glial cells help mitigate neurological damage in Huntingtons disease

The brain is not a passive recipient of injury or disease. Research has shown that when neurons die and disrupt the natural flow of information they maintain with other neurons, the brain compensates by redirecting communications through other neuronal networks. This adjustment or rewiring continues until the damage goes beyond compensation. This process of adjustment, […]

Small number of cells could be key enablers of cancer metastasis

Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists. Working with their research collaborators, the scientists found that ‘enabler cells’ comprise about 20 percent or less of the […]

How CD4+ T cells respond to SARS-CoV-2 in COVID-19 recovered patients

An international team of researchers from the Institute for Research in Biomedicine, affiliated to the Università della Svizzera italiana, has deciphered the T cell responses occurring during COVID-19 infection at single-cell resolution. This study, which was performed at the Center of Medical Immunology under the leadership of Prof. Federica Sallusto, included collaborations with clinical institutions […]

Newly discovered airway cells may shed light on SIDS and other conditions

Recent research links certain cells that line the human airway with different infant diseases. The work, which is published in Cell Reports and was led by investigators at Massachusetts General Hospital (MGH), could lead to new prevention and treatment strategies for these conditions. The human airway—from the windpipe to the lungs—is lined with epithelial cells, […]

Clinical trial assesses stem cells’ ability to prevent major cause of preemie deaths

A phase 2 clinical trial whose results were released today in Stem Cells Translational Medicine might point to a way to overcome bronchopulmonary dysplasia (BPD), a major cause of death in preterm infants. The study, conducted by researchers at Samsung Medical Center, Sungkyunkwan University and Asan Medical Center Children’s Hospital in Seoul, evaluates the effectiveness […]