In a study published in mBio, researchers from Ohio State University have been investigating mutations in the rest of the spike protein, particularly the Q677H mutation. Study: Neutralization of SARS-CoV-2 Variants of Concern Harboring Q677H. Image Credit: joshimerbin/ Shutterstock Background Since mass vaccination began, most worries about coronavirus disease 2019 (COVID-19) in developed countries focus […]
The number of Covid cases in the UK has risen 12% this week, but while some people may be hospitalized, others will suffer little more than a loss of smell. London Medical Laboratory says new research is now revealing everyone’s immune system is as unique as their fingerprint. Dr Quinton Fivelman PhD, Chief Scientific Officer […]
Researchers at the Paul Scherrer Institute PSI are the first to have joined two proteins together by means of a free-standing, rigid link. The structural element holds the two protein molecules together at a defined distance and angle, much the way a barbell handle connects two weights. This type of linkage could help, for example, […]
Natural infection or vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confer considerable protection against reinfection and reduce the risk of severe Coronavirus disease 2019 (COVID-19) outcomes. However, reports on decaying neutralizing antibody (Ab) levels against SARS-CoV-2 have raised questions regarding long-term immunity. Sporadic breakthrough infections have been reported after vaccination due to lower […]
The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, which has expanded its focus to include evaluating outpatient treatment for COVID-19, today announced positive data for the monoclonal antibody combination therapy BRII-196/BRII-198 from the ACTIV-2 study of Outpatient Monoclonal Antibodies and Other Therapies. In an interim analysis of the phase 3 evaluation […]
Researchers at the Francis Crick Institute and University College London Hospitals NHS Foundation Trust (UCLH) have studied whether antibodies produced as a result of infection with one SARS-CoV-2 variant are able to bind to and neutralize other variants. Over the course of the pandemic, various COVID-19 variants have arisen with the Delta variant currently dominant […]
In late December 2019, a novel coronavirus was first reported in Wuhan, China, which showed high infectivity and caused pneumonia-like symptoms. Scientists later identified this RNA virus as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Owing to rapid mutations, the continual emergence of several SARS-CoV-2 variants have been reported, among which some are […]
As a result of the ongoing pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease, the coronavirus disease 2019 (COVID-19), the global public health at risk has never been more dire. As a result of SARS-CoV-2 infection, antibodies are produced against a range of viral antigens, including the spike and […]
Scientists have reported that in most cases, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, mildly infects infants. However, around 10% of infants experienced severe COVID-19 infection who required advanced medical treatments. In rare cases, even asymptomatic infection can result in Multisystem Inflammatory Syndrome in […]
The rapid spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) pandemic. To date, the virus has claimed more than 3.8 million lives worldwide. The reverse transcriptase-polymerase chain reaction (RT-PCR) is considered the gold standard for detecting SARS-CoV-2 in upper and lower respiratory specimens as well as for […]
