Researchers identify new targets for minimizing tooth sensitivity to cold

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp containing nerves and blood vessels. We found that odontoblasts, which support the shape of the tooth, are also responsible for sensing cold. This research […]

Researchers evaluate long-term effectiveness of pessaries for treating pelvic organ prolapse

The aging population combined with increasing obesity rates has resulted in more women experiencing pelvic organ prolapse. Common treatment options include pelvic reconstructive surgery or the use of pessaries to prop up descending organs. A new study evaluated the long-term effectiveness of pessaries, as well as reasons why women discontinued their use. Study results are […]

Study: Patients should be assessed for frailty before considering multiple surgeries

Patients should be assessed for frailty before having many types of surgery, even if the surgery is considered low risk, a review of two national patient databases shows. Frailty is a clinical syndrome marked by slow walking speed, weak grip, poor balance, exhaustion and low physical activity. It is an important risk factor for death […]

Method to derive blood vessel cells from skin cells suggests ways to slow aging

Salk scientists have used skin cells called fibroblasts from young and old patients to successfully create blood vessels cells that retain their molecular markers of age. The team’s approach, described in the journal eLife on September 8, 2020, revealed clues as to why blood vessels tend to become leaky and hardened with aging, and lets […]

Researchers provide novel insights into primate arterial aging

Cardiovascular disorders are leading causes of morbidity and death worldwide. Age-associated changes in arterial properties, such as endothelial dysfunction and structural alterations, are considered to be initial events in the development of atherosclerosis. Due to the high heterogeneity of vascular cells from different sources, our understanding of human arterial aging and the development of interventions […]

Aging monocytes produce less energy, carry more inflammation markers

Healthy aging has become one of the priorities of research in Europe. University of Tartu researchers looked for differences in the immune systems of young and old people with a focus on monocytes; they found that the monocytes of the elderly do not seem to produce as much energy, and there is an increase in […]

Discovery may illuminate a missing link between atherosclerosis and aging

Investigators from Brigham and Women’s Hospital have made a potentially exciting discovery by jumping into the abyss of the dark side of the genome. Once dismissed as “junk DNA,” roughly 75 percent of the human genome do not code for proteins. But these dark regions of the genome are far from junk—instead, they may hold […]

Living with an optimistic partner may lower your risk of dementia

A recent study published in the International Journal of Behavioral Development found having an optimistic spouse might cut your risk of developing dementia.  According to the study, a positive partner could help combat some of the risk factors for Alzheimer's and dementia and promote healthy practices like maintaining a balanced diet, staying active, and overall […]