CDK9 inhibitors: A promising new treatment for hematological malignancies

Reviewers’ Notes A new research perspective was published in Oncotarget's Volume 14 on August 7, 2023, entitled, "CDK9 INHIBITORS: a promising combination partner in the treatment of hematological malignancies." In their new perspective, researchers Daniel Morillo, Gala Vega and Victor Moreno from Hospital Fundación Jiménez Díaz discuss Cyclin-dependent kinases (CDK) in hematological malignancies. CDKs belong […]

Health care utilization up with childhood stressful life events

Stressful life events (SLEs) in childhood, including emotional abuse, unmet basic needs, experiences of racism, household mental illness, household substance abuse, parental incarceration, and exposure to neighborhood violence, are associated with increased health care utilization and unmet medical care needs, according to a study published online Aug. 8 in the National Health Statistics Reports, a […]

Exercise apps could be a major tool to combat mental health crisis among healthcare workers

Reviewers’ Notes Simple home workouts using exercise apps can effectively reduce depressive symptoms in healthcare workers and could be a major tool to combat the global mental health crisis in the sector, says new University of British Columbia research. The study, published today in JAMA Psychiatry, divided participants into either a waitlisted control group or […]

Childhood cancer: New immune system responds better to therapy

Scientists at St. Anna Children’s Cancer Research Institute and the Eberhard Karls University of Tübingen have shown that immunotherapy after stem cell transplantation effectively combats certain nerve tumors in children. Crucially, stem cells from a parent provide children with a new immune system that responds much better to immunotherapies. These results of an early clinical […]

The temperature the human body cannot survive

Scientists have identified the maximum mix of heat and humidity a human body can survive. Even a healthy young person will die after enduring six hours of 35-degree Celsius (95 Fahrenheit) warmth when coupled with 100 percent humidity, but new research shows that threshold could be significantly lower. At this point sweat—the body’s main tool […]

CT imaging reveals that COVID-19 vaccination may protect against severe lung pathology

The rapid worldwide transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to the coronavirus disease 2019 (COVID-19) pandemic. Since the start of the pandemic, scientists worked at an unprecedented pace to develop effective vaccines to protect individuals from contracting this infection. Despite the availability of vaccines and a high vaccination rate, the […]

Peoples everyday pleasures may improve cognitive arousal and performance

Listening to music and drinking coffee are the sorts of everyday pleasures that can impact a person’s brain activity in ways that improve cognitive performance, including in tasks requiring concentration and memory. That’s a finding of a new NYU Tandon School of Engineering study involving MINDWATCH, a groundbreaking brain-monitoring technology. Developed over the past six […]