Exercise really can help you sleep better at night—heres why that may be

Many people struggle to get enough good quality sleep. Not only does this leave us feeling tired the next day, but over the long term poor sleep can actually have a negative effect on other aspects of our health and well-being. There’s no shortage of things people are told they can do to get a […]

Adjunct minocycline no benefit for treatment-resistant depression

For patients with treatment-resistant depression (TRD), minocycline as add-on to antidepressant treatment as usual does not reduce depressive symptoms, according to a study published online Sept. 14 in JAMA Network Open. Julian Hellmann-Regen, M.D., from Charité—Universitätsmedizin Berlin, and colleagues conducted a trial involving patients with TRD who were randomly assigned to receive adjunct minocycline or […]

Weight loss benefits highly dependent on starting BMI, study finds

A new study finds that the success of weight-loss methods depends on your starting body weight. Of the groups studied, people with obesity benefited the most from all weight-loss methods, gaining the least weight afterward and lowering their risk of developing type 2 diabetes. However, people who are already lean when they lose weight may […]

New way to prevent heart complications in children with Kawasaki disease

Researchers have identified a new way to treat young children with Kawasaki disease (KD) to prevent life-threatening coronary artery damage and heart attacks. The WEHI-led study showed that treatment with drugs called mTOR inhibitors can prevent the formation of coronary artery damage and aneurysms, a much-feared complication of KD. Importantly, mTOR inhibitors are already known […]

Effectiveness of antipsychotics dips for women after age 45 years, says study

Antipsychotic effectiveness declines in women after the age of 45 years, according to a study published online Oct. 5 in Schizophrenia Bulletin. Iris E. Sommer, M.D., Ph.D., from the University Medical Center Groningen in the Netherlands, and colleagues used Finnish nationwide registers (61,889 individuals) to identify persons with schizophrenia/schizoaffective disorder and stratify by sex and […]

Most preprint studies of COVID-19 hold up through peer-review: study

Research findings posted online as preprints—studies made public before undergoing the review and approval of a panel of peer scientists required by most scholarly journals—often hold up quite well to that scrutiny, according to a new report on COVID-19 studies. While preprint manuscripts have become popular in many scientific fields since physicists made their arXiv […]

New generation of weight loss medications offer promise—but at a price

Excitement is building about a new generation of drugs that tout the ability to help adults with excess weight shed more pounds than older drugs on the market. Some patients, obesity medicine specialists say, are experiencing decreases in blood pressure, better-managed diabetes, less joint pain, and better sleep from these newfound treatments. The newer drugs, […]

GAVI Financing to Allow for Immediate Funds for Next Pandemic

(Reuters) – Global vaccine alliance GAVI has set up financial instruments that will allow the group to immediately access pledged donor funding if it needs to buy vaccines for future pandemics, Chief Executive Seth Berkley told Reuters. Berkley said that in 2020 and 2021, GAVI was limited in its ability to buy COVID-19 vaccines because […]