Macrophages That Heal Intestinal Inflammation Are Promising Target for IBD Therapy

NEW YORK (Reuters Health) – A subset of macrophages, PTGER4+ (EP4+), are the major drivers of epithelial regeneration after intestinal inflammation and are potential targets for inflammatory bowel disease (IBD) therapy, researchers say. “Dysfunctional resolution of intestinal inflammation and altered mucosal healing are essential features in the pathogenesis of IBD,” Dr. Gianluca Matteoli of KU […]