Supplementing testosterone significantly reduces heart attacks and strokes in men with unnaturally low levels of the hormone, according to new research presented at the European Association of Urology congress today. The ten-year study involved over 800 men from Germany and Qatar with testosterone deficiency, whose family history, blood pressure, cholesterol levels, diabetes or weight put […]
Gene therapy in early stages may slow down Huntingtons disease
In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington’s disease, a neurodegenerative disorder that attacks brain cells. The researchers say that by identifying and […]
Radioligand therapy slows advanced PSMA+ prostate cancer
(HealthDay)—Lutetium-177 (177Lu)-prostate-specific membrane antigen (PSMA)-617 radioligand therapy added to standard care is beneficial for patients with advanced PSMA-positive metastatic castration-resistant prostate cancer, according to a study published online June 23 in the New England Journal of Medicine. Oliver Sartor, M.D., from Tulane University in New Orleans, and colleagues conducted an international, phase 3 trial involving […]
Statin therapy not associated with cognitive decline, dementia in older adults, study says
The use of statin therapy in adults 65 years old or older is not associated with incident dementia, mild cognitive impairment (MCI) or decline in individual cognition domains, according to a study published in the Journal of the American College of Cardiology (JACC). Cognitive decline and dementia are major health concerns in older individuals, affecting […]
Replacing what was lost: A novel cell therapy for type I diabetes mellitus
Type I diabetes mellitus (T1D) is an autoimmune disorder leading to permanent loss of insulin-producing beta-cells in the pancreas. In a new study, researchers from the University of Tokyo developed a novel device for the long-term transplantation of iPSC-derived human pancreatic beta-cells. T1D develops when autoimmune antibodies destroy pancreatic beta-cells that are responsible for the […]
Combination therapy may provide significant protection against lethal influenza
A significant proportion of hospitalized patients with influenza develop complications of acute respiratory distress syndrome, driven by virus-induced cytopathic effects as well as exaggerated host immune response. Reporting in The American Journal of Pathology, investigators have found that treatment with an immune receptor blocker in combination with an antiviral agent markedly improves survival of mice […]
U.S. FDA Approves Yescarta for Relapsed or Refractory Follicular Lymphoma After Two or More Lines of Systemic Therapy
SANTA MONICA, Calif.–(BUSINESS WIRE)–Mar. 5, 2021– Kite, a Gilead Company (Nasdaq: GILD), today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval to Yescarta® (axicabtagene ciloleucel) for the treatment of adult patients with relapsed or refractory follicular lymphoma (FL) after two or more lines of systemic therapy. The approval makes Yescarta the first chimeric antigen receptor […]
A Doctor Explained the Truth About The Rock’s Recent ‘Cupping’ Therapy
Dwayne “The Rock” Johnson regularly shares updates relating to his workouts and nutrition, and has upped the intensity and rigor in his training and diet recently as he prepares to start filming DC’s Black Adam. In an Instagram photo posted this week, Johnson showed off his back, which was covered in red, sore-looking circular bruises […]
CAR T-cell therapy generates lasting remissions in patients with multiple myeloma
In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found. In a study posted online today by the New England Journal of Medicine, trial leaders report that almost 75% of the […]
First-in-human clinical trial to assess gene therapy for Alzheimer’s disease
Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia. The […]