Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences. The authors summarize evidence supporting a strong relationship between ceramides and a range of diseases in animals and humans and compare it to the decades of datasets that […]

New study aims to develop alternative treatment for posterior eye diseases

Getting poked in the eye with a sharp object is a cringeworthy thought. However, many patients with posterior eye diseases — back of the eye diseases such as macular degeneration or diabetic retinopathy — undergo eye injections through the wall of the eye as a medical treatment on a regular basis. "Direct injections of medications […]

Botulism breakthrough? Taming botulinum toxin to deliver therapeutics

While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum—the most potent toxins known. These toxins are often found in contaminated food (home canning being a major culprit). Infants can also develop botulism from ingesting C. botulinum spores in honey, soil, or dust; the bacterium […]

Coronavirus therapeutics 'more complicated' than vaccine, expert says

WHO warns of surge in coronavirus cases in Europe EEurope is seeing more weekly coronavirus cases than it did in March’s peak; Amy Kellogg reports. Editors of a highly respected medical journal discussed on Wednesday "Operation Warp Speed" and the government's response to COVID-19, focusing mostly on therapeutics. "Operation Warp Speed" is the U.S. government's plan to […]