Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences. The authors summarize evidence supporting a strong relationship between ceramides and a range of diseases in animals and humans and compare it to the decades of datasets that […]
New study aims to develop alternative treatment for posterior eye diseases
Getting poked in the eye with a sharp object is a cringeworthy thought. However, many patients with posterior eye diseases — back of the eye diseases such as macular degeneration or diabetic retinopathy — undergo eye injections through the wall of the eye as a medical treatment on a regular basis. "Direct injections of medications […]
Researchers uncover 'hotspots' on the Spike protein that are critical for SARS-CoV-2 infection
The COVID-19 pandemic has prompted considerable investigation into how the SARS-CoV-2 Spike protein attaches to a human cell during the infection process, as this knowledge is useful in designing vaccines and therapeutics. Now, a team of scientists has discovered additional locations on the Spike protein that may not only help to explain how certain mutations […]
Botulism breakthrough? Taming botulinum toxin to deliver therapeutics
While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum—the most potent toxins known. These toxins are often found in contaminated food (home canning being a major culprit). Infants can also develop botulism from ingesting C. botulinum spores in honey, soil, or dust; the bacterium […]
Coronavirus therapeutics 'more complicated' than vaccine, expert says
WHO warns of surge in coronavirus cases in Europe EEurope is seeing more weekly coronavirus cases than it did in March’s peak; Amy Kellogg reports. Editors of a highly respected medical journal discussed on Wednesday "Operation Warp Speed" and the government's response to COVID-19, focusing mostly on therapeutics. "Operation Warp Speed" is the U.S. government's plan to […]
With many regulatory barriers clear, remaining roadblocks for digital therapeutics are cultural, logistical
While some of the more obvious barriers to digital therapeutics adoption in Europe have come crashing down recently, adoption is still hampered by cultural momentum. That was the conclusion of a group of digital therapeutics stakeholders who presented at HIMSS & Health 2.0 Europe Digital Event today, in a session moderated by YourCoach Health chairman and […]