Insulin resistance doubles risk of major depressive disorder, study finds

Stanford Medicine scientists have linked insulin resistance to an increased risk of developing major depressive disorder. “If you’re insulin-resistant, your risk of developing major depressive disorder is double that of someone who’s not insulin-resistant, even if you’ve never experienced depression before,” said Natalie Rasgon, MD, Ph.D., professor of psychiatry and behavioral sciences. Upward of 1 […]

These Resistance Band Exercises Can Help You Build Bigger, Stronger Shoulders

In the latest in the Athlean-X series of weight-free workout videos, Jeff Cavaliere C.S.C.S. demonstrates a series of resistance band exercises that can help build bigger, stronger shoulders. “Never underestimate the power of resistance bands in building muscle if you know how to use them,” he says. You can add any of these dozen exercises […]

Novel combination therapy may help overcome mTOR drug resistance in AML

Soon after rapamycin, the first mTOR inhibitor, emerged in 1990s as a potential treatment against unwanted cell proliferation, many cancer experts had hoped emerging drugs targeting mTOR would become a breakthrough targeted therapy for children and adults suffering relapses of acute myeloid leukemia (AML) and other cancers where mTOR activity is abnormally high. However, numerous […]

High-intensity resistance training in post-acute care produced better outcomes and patient experience

Today, researchers from the University of Colorado Anschutz Medical Campus released a new study evaluating the effectiveness and safety of high-intensity rehabilitation for older adults in skilled nursing facilities. The study was published today in Physical Therapy. Skilled nursing facilities provide medical and rehabilitation services to individuals post-hospitalization to help facilitate the transition to home […]

Gene targeting overcomes the resistance of brain cancer to therapy

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma. A McGill-led study published in Nature Communications reveals that suppressing the OSMR gene can improve the effectiveness of radiation therapy. This approach, led by the laboratory of Arezu Jahani-Asl, Assistant […]

New drug could reverse treatment resistance in advanced multiple myeloma

Researchers at the VU University Medical Center in the Netherlands have tested a new drug in patient samples and mice with multiple myeloma and discovered that it was effective even in advanced disease—a point when many patients currently run out of options. These promising results could pave the way for the new drug to be […]

‘Genetic rewiring’ drives cancer’s drug resistance

A tiny molecule of RNA—known as ‘micro RNA’ – plays a key role in ‘rewiring’ cancer cells so they can resist the effects of chemotherapy, a new study reveals. The discovery opens up the possibility of creating new cancer drugs that target this micro RNA molecule, rather than more conventional treatments that block the action […]

Double success for drug resistance research

Swansea University research into the threat posed by antifungal drug resistance has been highlighted in two prestigious international journals. Fungal disease now kills more people than malaria or TB and the Centre for Disease Control in the USA recognises emergence of multi-drug resistance in fungi as a high level threat. Dr. Josie Parker and Prof […]