Simple blood test could tell if you’re going to be struck down with dementia in the next five years, experts say Patients have suffered brain damage when first symptoms of dementia appear But scientists say they may soon be able to diagnose the condition early This would lead to faster treatment for patients, helping to […]
Breast cancer researchers learn how to teach an old drug new tricks to help patients
Paclitaxel, or Taxol, is an old standby drug in the oncologist’s tool belt. Yet only about half of breast cancer patients treated with the drug see their tumors shrink or disappear, and doctors and researchers have no way of knowing which patients will benefit. But that may soon change. Published Sept. 8 in Science Translational […]
Researchers release masks that instantaneously deactivate SARS-CoV-2
The Catholic University of Valencia and Valencian company Visor Medical, manufacturer of preventive health technology for innovation, have released a type IIR surgical mask with an intelligent fabric that can instantaneously deactivate the SARS-COV-2 virus that is responsible for COVID19. The intelligent fabric of these masks has been created thanks to the work of a […]
Researchers develop all-in-one test for the avoidance of de novo genetic disease in embryos
De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have. Where a disease-causing DNV is present in one parent, the risk of passing it to a child can be as high as 50% and being able […]
Researchers uncover the biology and treatment behind a rare autoinflammatory disease
The absence of a protein that activates the body’s antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found. The condition, which is now termed TBK1 deficiency, was previously known […]
Researchers find important clue to rare inflammatory disease in children following COVID-19 infection
Mount Sinai researchers have found an important clue to a rare but serious aftereffect of COVID-19 in children, known as multisystem inflammatory syndrome in children or MIS-C. The researchers reported that RNA sequencing of blood samples from the Mount Sinai COVID-19 Biobank led to the discovery that specific infection-fighting cells of the immune system are […]
Researchers uncover a way to harness the power of immunotherapy for advanced prostate cancer
It’s a scientific riddle tangled up in a complex web. How do you turn an immune cold cancer into one that responds to immunotherapy? Researchers led by the University of Michigan Rogel Cancer Center started with a simple thread: an inhibitor that showed promise against metastatic castration-resistant prostate cancer cells. This is the most challenging […]
Researchers identify signaling molecule that may help prevent Alzheimers disease
New research in humans and mice identifies a particular signaling molecule that can help modify inflammation and the immune system to protect against Alzheimer’s disease. The work, which was led by investigators at Massachusetts General Hospital (MGH), is published in Nature. Cognitive decline associated with Alzheimer’s disease develops when neurons begin to die. “Neuron death […]
Researchers: HtrA1 augmentation is potential therapy for age-related macular degeneration
Research conducted at the Sharon Eccles Steele Center for Translational Medicine (SCTM) at the University of Utah’s John A. Moran Eye Center explains why people carrying a block of genetic variants strongly associated with the development of age-related macular degeneration (AMD) may develop the disease and identifies a potential therapeutic pathway for slowing or even […]
Researchers clarify the role of the two isoforms of KRAS, the most common oncogene in humans
KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common drivers of cancer and its mutations can be detected in around 25 percent of human tumors. The development of KRAS inhibitors is, thus, an extremely active line of research. Effective results have been elusive so […]