Prior to the emergence of new mutants of the coronavirus, such as the British variant B.1.1.7, the SARS-CoV-2 variant named D614G had already mutated from the original SARS-CoV-2 pathogen that triggered the pandemic. D614G has rapidly spread to become the most abundant variant worldwide and this D614G mutation remains in all the new emerging variants. […]
A Mason Engineering researcher has discovered that artificial microswimmers accumulate where their speed is minimized, an idea that could have implications for improving the efficacy of targeted cancer therapy. Jeff Moran, an assistant professor of mechanical engineering in the Volgenau School of Engineering, and colleagues from the University of Washington in Seattle studied self-propelled half-platinum/half-gold […]
Researchers at the University of Maryland School of Medicine (UMSOM) co-authored a study, published today in the journal Science, that details the sequencing of 64 full human genomes. This reference data includes individuals from around the world and better captures the genetic diversity of the human species. Among other applications, the work will enable population-specific […]
Low blood levels of immune cells called lymphocytes, in combination with higher levels of inflammation on PET/CT scans, are indicators of active sarcoidosis — an inflammatory disease that attacks multiple organs, particularly the lungs and lymph nodes — which disproportionately affects African Americans. The discovery by researchers at the University of Illinois Chicago could help […]
In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found. In a study posted online today by the New England Journal of Medicine, trial leaders report that almost 75% of the […]
Numerous psychiatric studies have documented increased rates of depression and anxiety among those forced to relocate, with sudden moves often affecting individuals' social support and sense of identity and control. As the COVID-19 pandemic spread through the U.S. in March of 2020, universities evacuated students from their campuses, and thousands quickly relocated. Few studies have […]
At an online European Parliament workshop hosted by Deirdre Clune MEP (Ireland), Alzheimer Europe launched a new report "Data Sharing in Dementia Research", which reviews recent changes in EU research policy and sets out recommendations to improve data sharing in dementia research. In this report, Alzheimer Europe evaluates the legal and policy landscapes that dementia […]
The COVID-19 pandemic has prompted considerable investigation into how the SARS-CoV-2 Spike protein attaches to a human cell during the infection process, as this knowledge is useful in designing vaccines and therapeutics. Now, a team of scientists has discovered additional locations on the Spike protein that may not only help to explain how certain mutations […]
Disorders of cellular energy supply can cause a number of serious diseases, but also seem to be connected to aging. More research is needed on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects their function in mice and fruit flies. […]
Extending the symptoms that trigger a PCR test for COVID-19 could help detect around a third more cases of the disease. New research led by researchers at King's College London and published in the Journal of Infection suggests that restricting testing to the 'classic triad' of cough, fever and loss of smell which is required […]
