A promising path for future treatments to stop progressive multiple sclerosis

Researchers at the National Institutes of Health, Johns Hopkins University, and others have published results of studies that map out the activity of genes, molecules, cells, and their interactions in specific types of multiple sclerosis (MS) brain lesions thought to contribute to progressive disability. The findings point to a possible informative new way to efficiently […]

Promising new target for urinary tract infections and kidney stones

Researchers from Tokyo Medical and Dental University (TMDU) have found that the secretion of uromodulin protein into urine can be induced by treatments that may protect against urinary tract infections and kidney stones, among other diseases The normal function of uromodulin, a protein that is made in the kidney and secreted into the urine, remains […]

Microneedles are promising devices for painless drug delivery with minimal side effects

A recent study from the University of Helsinki monitors the breakthrough progresses in the development of microneedles for immunotherapy and discusses the challenges regarding their production. Researchers suggest using microneedles for immunotherapy due to the high abundance of immune cells under the skin. The aim is to vaccinate or treat different diseases, such as cancer […]

Study shows clamp technology promising for future vaccine development

University of Queensland scientists have published the clinical trial data confirming their molecular clamp-stabilized vaccine technology was safe and potentially effective. The vaccine candidate developed by the team last year did not progress through to Phase 2/3 clinical trials, due to cross reactivity caused by the protein fragment used to stabilize the clamp design. Initial […]

Oral COVID treatment yields promising trial data: drugmakers

Pharmaceutical giant Merck and an American laboratory reported promising results Saturday in trials of a drug administered orally to fight COVID-19, saying it helps reduce patients’ viral load. “At a time where there is unmet need for antiviral treatments against SARS-CoV-2, we are encouraged by these preliminary data,” said Wendy Painter, chief medical officer of […]

Drug is promising against pancreatic and breast cancers

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also […]

Music therapy feasibility study proves promising in cancer care

The principles of a music education approach for children show promise when used as the basis for music therapy with adult cancer patients. That is the conclusion of a feasibility study co-written by Cindy Colwell, University of Kansas professor of music, and Jennifer Fiore, a KU alumna and current faculty member at Western Michigan University, […]

Researchers identify promising drug combination for melanoma

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer. Lead author Amanda Truong, trainee in the McMahon Lab at HCI and student at the U of U, explains uveal melanoma patients frequently have changes in […]

A promising therapeutic modality against the coronavirus

Since the emergence of the novel coronavirus in late 2019, multiple approaches for treating COVID-19 have been considered, from the use of repurposed medicines such as the antimalarial drug, hydroxychloroquine, to the Ebola antiviral drug, remdesivir. Many of these therapeutic strategies have fallen short in terms of their clinical effectiveness, which has propelled scientists to […]

Investigational ALS drug generates promising clinical trial results

An experimental medication slows the progression of the neurodegenerative disease called Amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, according to recently released results from a clinical trial run by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH) and Amylyx Pharmaceuticals, Inc., the company that manufactures the […]