New drug shows real promise against celiac disease

An experimental drug can prevent intestinal damage caused by celiac disease, an early trial has found—raising hopes that it could become the first medication for the serious digestive disorder. With celiac disease, the immune system attacks the lining of the small intestine when a genetically susceptible person eats gluten—a protein found in wheat, rye and […]

Arthritis drug shows promise against severe COVID: study

A repurposed arthritis drug has shown positive results in a clinical trial of patients hospitalized with COVID-19, according to a paper published Wednesday in the New England Journal of Medicine. Tofacitinib, taken orally and sold under the brand name Xeljanz among others, was tested in a trial of 289 patients hospitalized with severe COVID across […]

New combination of immunotherapies shows great promise for treating lung cancer

McMaster University researchers have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer. The new treatment, yet to be tested on patients, uses one form of therapy to kill a significant number of […]

Prototype graft, designed to replace damaged heart vessels, shows promise in cell study

In a proof-of-concept study, North Carolina State University researchers reported promising preclinical findings for a prototype of a vascular graft designed as a replacement for a damaged or blocked coronary artery, which supplies blood to the heart. The findings, which were made in partnership with researchers from Case Western Reserve University, are part of an […]

Scientists identify 21 drugs that show promise for treating COVID-19

Scientists identify 21 drugs that show promise for treating COVID-19 – including four that might be used with remdesivir to combat the virus Researchers at Sanford Burnham Prebys Medical Discovery Institute in California screened 12,000 drugs for potential to fight coronavirus They found 21 – including remdesivir, which had not yet been given emergency approval – […]

New vitamin K-based drug shows promise against medication-resistant epilepsy

In the cover article of the June 11 issue of the Journal of Medicinal Chemistry, a team of researchers at the Medical University of South Carolina, led by Sherine Chan, Ph.D., and James Chou, Ph.D., reports that a new vitamin K-based drug has proved effective in mouse models of medication-resistant seizures. Chan and Chou, both […]

Pfizer's coronavirus shot shows promise by triggering immune response

Experimental coronavirus vaccine from Pfizer triggered levels of antibodies up to THREE TIMES greater than those seen in recovered patients, early data shows Researchers randomly gave 45 healthy volunteers either a low dose, a medium dose or a high dose of a coronavirus vaccine, or a placebo Those who received the vaccine were given two shots, except […]

In early trial, an ancient drug shows promise against severe COVID-19

There’s new evidence that a 2,000-year-old medicine might offer hope against a modern scourge: COVID-19. The medication, called colchicine, is an anti-inflammatory taken as a pill. It’s long been prescribed for gout, a form of arthritis, and its history goes back centuries. The drug was first sourced from the autumn crocus flower. Doctors also sometimes […]

Fecal transplants show promise as treatment for non-alcoholic fatty liver disease

A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease (NAFLD). The randomized controlled trial published in the American Journal of Gastroenterology found that fecal transplants in patients with NAFLD result in a reduction in how easily pathogens and […]

Small study suggests COVID-19 antibody test shows promise

A test that can detect the presence of antibodies to the SARS-CoV-2 virus in the blood of human patients is described in Nature Medicine. This assay, tested in 16 patients, may help to identify individuals whose plasma contains antibodies to SARS-CoV-2, which could potentially be used to treat other patients. Tests that detect the presence […]