Researchers have identified a potential new treatment that suppresses the replication of SARS-CoV-2, the coronavirus that causes COVID-19. In order to multiply, all viruses, including coronaviruses, infect cells and reprogram them to produce novel viruses. The research revealed that cells infected with SARS-CoV-2 can only produce novel coronaviruses when their metabolic pentose phosphate pathway is […]
(HealthDay)—Receipt of the Ad26.COV2.S (Janssen/Johnson & Johnson) COVID-19 vaccine is associated with a potential small, but statistically significant, safety concern for Guillain-Barré syndrome (GBS), according to a study published online Oct. 7 in the Journal of the American Medical Association. Emily Jane Woo, M.D., M.P.H., from the U.S. Food and Drug Administration in Silver Spring, […]
The arachnoid is one of the three meninges, or brain membranes, and is responsible for mechanically and immunologically protecting the brain and the spinal cord. It allows communication between the cerebrospinal fluid (which bathes the brain and the spinal cord) and the cerebral blood vessels, and controls several crucial physiological responses in the brain, such […]
Although two SARS-CoV-2 variants are associated with higher transmission, patients with these variants show no evidence of higher viral loads in their upper respiratory tracts compared to the control group, a Johns Hopkins School of Medicine study found. The emergence and higher transmission of the evolving variants of SARS-CoV-2, the virus that causes COVID-19, has […]
A new study reveals that renin-angiotensin system (RAS) genes within the amygdala—the brain region important for traumatic memory processing—express differently when the brain develops fearful memories, such as when people undergo traumatic stress. Researchers have found that medication may potentially be used as a pharmacological blockade of the angiotensin type 1 receptor, thereby improving components […]
Alzheimer’s disease treatments that slow progression of the disease could significantly reduce the financial burden to U.S. state budgets, according to a new USC study. The study outlines how states—which have been hit particularly hard by the COVID-19 pandemic—would see relief: Medicare would cover the costs of treating the disease, while Medicaid expenditures would be […]
New data from Addenbrooke’s Hospital in Cambridge suggests that a single dose of the Pfizer BioNTech vaccine can reduce by four-fold the number of asymptomatic SARS-CoV-2 infections. This implies that the vaccine could significantly reduce the risk of transmission of the virus from people who are asymptomatic, as well as protecting others from getting ill. […]
Immunologists at St. Jude Children’s Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism does not affect regulatory T cell function outside the tumor and may therefore limit the immune-associated toxicities of targeting regulatory T cells. […]
As reported in Nature Communications, researchers from Cleveland Clinic’s Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease. The team used the model to identify a promising target that could be inhibited to slow disease progression.Ulcerative colitis is […]
Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn’t tell you everything about your immunity. The levels and even types of antibodies can differ among patients, and those differences can influence whether a person is protected against being reinfected. Scientists at The Ohio State University have developed a new lab […]
