Five years ago, the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and National Cancer Institute (NCI), part of the National Institutes of Health, jointly launched a very different kind of cancer study. NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131), the largest precision medicine cancer trial to date, sought to match genetic abnormalities driving patients’ tumors with […]
In a clinical trial testing two different forms of “nudging,” statin prescriptions at the right dosages increased significantly among patients with heart disease when doctors had to actively choose whether or not to prescribe the medications, which are used to lower cholesterol. However, for patients who were just deemed at-risk for heart disease, neither an […]
Sitagliptin, a drug to lower blood sugar in type 2 diabetes, also improves survival in diabetic patients hospitalized with COVID-19, suggests a multicenter observational study in Italy. Patients given sitagliptin in addition to insulin had a mortality rate of 18 percent as compared with 37 percent in matched patients receiving only insulin. Led by Paolo […]
Physicians and researchers at the Perelman School of Medicine at the University of Pennsylvania, the Corporal Michael J. Crescenz VA Medical Center, VA Connecticut Healthcare System, and Beth Israel Deaconess Medical Center created a new prediction model which, when compared to older and widely-used models, provided better estimated risk of mortality after surgery for patients […]
Researchers at the University of East Anglia have been putting virtual reality rehabilitation for stroke survivors to the test. They have created a new gaming platform which uses low cost videogame technology to improve the lives of stroke patients suffering from complex neurological syndromes caused by their stroke. And they have been working with stroke […]
Severe mental illness diagnoses are missed by clinicians in more than one quarter of cases when people are hospitalised for other conditions, finds a new study led by UCL researchers. People from ethnic minority groups are even more likely to have previously diagnosed mental illnesses go unnoticed by medical staff, according to the findings from […]
A Cambridge hospital has piloted the use of combined rapid point-of-care nucleic acid and antibody testing for SARS-CoV-2 infection after researchers at the University of Cambridge showed that this approach was superior to virus detection alone for diagnosing COVID-19 disease. Point-of-care testing—in other words, testing patients as soon as they arrive at the hospital—is essential […]
More than half of patients hospitalized with suspected COVID-19 in Michigan during the state’s peak months received antibiotics soon after they arrive, just in case they had a bacterial infection in addition to the virus, a new study shows. But testing soon showed that 96.5% of them only had the coronavirus, which antibiotics don’t affect. […]
Ten post-mortem examinations performed on patients with confirmed COVID-19 found that all patients had lung injuries and early scarring of the lungs as a result of the virus, as well as injury to their kidneys. Nine patients also had thrombosis—a blood clot- in at least one major organ (heart, lung or kidney). The team were […]
Figure 1: A novel genetic locus related to interstitial lung disease was identified following genomic analysis of 5,000 rheumatoid arthritis patients. Credit: Osaka University In many cases, a complex interplay between our genes and the environment governs whether or not we will develop a certain disease. Interestingly though, researchers are discovering that the genetic component […]
