How cancers metastasize remains poorly understood. The process begins when cancer cells break off from a tumor and invade blood and lymphatic vessels, the body’s alleyways. But studying invasion—typically a microscopic process—is challenging. However, some types of tumors can invade blood vessels and form larger masses. By focusing on kidney cancer, a tumor that bulldozes […]
Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder, causes fluid-filled cysts to develop on the kidneys, which can impair their function. As part of the growth of cysts, the kidneys develop inflammation and fibrosis, or scarring. The disease is most often caused by a mutation in one of two genes, PKD1 or PKD2, which […]
A research team led by David Thanassi, PhD, of Stony Brook University, has used molecular biology and cryoelectron microscopy to successfully unravel the structure of bacterial appendages called P pili. These pili are deployed by uropathogenic strains of Escherichia coli bacteria that cause kidney infections. The structure of P pili had been elusive to scientists […]
Focal segmental glomerulosclerosis (FSGS) is a rare form of kidney inflammation (glomerulonephritis) in which the glomeruli become increasingly scarred (sclerotic), leading to progressive loss of kidney function. Dysregulation of the immune system plays a role in pathogenesis, which is why immunosuppressive therapy with glucocorticoids can be successful, alongside supportive therapy (especially blocking of the renin-angiotensin […]
An estimated 1 in 10 people worldwide have chronic kidney disease, but most of them don’t know it. That lack of awareness is especially concerning because people with chronic kidney disease who are infected with COVID-19 are at higher risk for serious illness. It is important that people understand their risk for developing chronic kidney […]
Patients with advanced kidney cancer, who received a targeted drug combined with a checkpoint-blocker immunotherapy agent had longer survival than patients treated with the standard targeted drug, said an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial. The survival benefit demonstrates that an immune checkpoint inhibitor together with a targeted […]
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. TARGOCID® teicoplanin Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about Targocid. It does not contain all the available information. It does not take the place of talking to your doctor, or pharmacist. All medicines have […]
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. CHEMMART TRAMADOL SR Contains the active ingredient, tramadol (as tramadol hydrochloride) Consumer Medicine Information What is in this leaflet Read this leaflet carefully before taking your medicine. This leaflet answers some common questions about tramadol. It does not contain all the available […]
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. VALGANCICLOVIR MYLAN contains the active ingredient valganciclovir CONSUMER MEDICINE INFORMATION What is in this leaflet This leaflet answers some common questions about VALGANCICLOVIR MYLAN tablets. It does not contain all the available information. It does not take the place of talking to […]
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. APO-AMOXYCILLIN AND CLAVULANIC ACID 875MG/125MG Amoxicillin trihydrate and potassium clavulanate Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about amoxycillin and clavulanic acid. It does not contain all the available information. It does not take […]
