Glutamate is the messenger substance the brain uses to pass on excitatory signals. Receptors for this neurotransmitter are a promising target for drug development, as they are involved in many pathological processes. For example, they play a role in epilepsy, mental disorders, strokes and brain tumors. “In these cases, it may be beneficial to reduce […]
Consistent signs of compromised inhibition found in a study of concussion sufferers were mirrored in separate tests on Canadian university football players. These findings open new doors to predicting the impact of the often debilitating injury, as well as raise questions about the long-term impact of contact sports, according to Western researchers. The study, “Concussion […]
Disrupting the production of a class of lipids known as sphingolipids in neurons improved symptoms of neurodegeneration and increased survival in a mouse model, according to new research led by the joint laboratory of Robert Farese, Jr. and Tobias Walther at Harvard T.H. Chan School of Public Health and Howard Hughes Medical Institute. The findings, […]
(HealthDay)—Inhibition of interleukin-1β (IL-1β) with canakinumab is associated with reduced incident anemia as well as improved hemoglobin levels among patients with baseline anemia, according to research published online March 24 in the Annals of Internal Medicine. Mounica Vallurupalli, M.D., from Brigham and Women’s Hospital in Boston, and colleagues conducted an exploratory analysis of a multicenter […]
