We are currently witnessing the ability of vaccination programs to limit the burden of infectious disease on both individuals and society. Despite their success, most vaccines are not completely effective, and efficacy varies significantly due to individual immune response but also age and other factors. Understanding the cellular and molecular interactions that lead to a […]
Scientists at the National Institutes of Health determined that stomach inflammation is regulated differently in male and female mice after finding that androgens, or male sex hormones, play a critical role in preventing inflammation in the stomach. The finding suggests that physicians could consider treating male patients with stomach inflammation differently than female patients with […]
Alzheimer's disease (AD) is a form of progressive dementia interfering with daily living. It is caused by the decline in the number of brain cells resulting in the deterioration of our mental abilities. One of the main reasons for the worsening brain cells condition and even the brain shrinkage are molecules having a specific structure […]
Some patients with moderate to severe COVID-19 disease seem to experience inflammation of the thyroid gland that is different from thyroid inflammation caused by other viruses, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting. One-third of the study participants still had signs of thyroid inflammation after three months, even […]
TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models. They found that TARM1 activated dendritic cells, and development of collagen-induced arthritis (CIA) was notably […]
Inflammation in the body has been linked to the intensity of tobacco smoking among people with HIV, according to a team of University of Massachusetts Amherst researchers. Krishna Poudel, associate professor of community health education in the School of Public Health and Health Sciences, and colleagues reported positive linear relationships between intensity, duration and pack-years […]
Low blood levels of immune cells called lymphocytes, in combination with higher levels of inflammation on PET/CT scans, are indicators of active sarcoidosis — an inflammatory disease that attacks multiple organs, particularly the lungs and lymph nodes — which disproportionately affects African Americans. The discovery by researchers at the University of Illinois Chicago could help […]
The coronavirus disease 2019 (COVID-19) pandemic has claimed well over 2.4 million lives, but its long-term sequelae are still being identified. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an infection that may be associated with a wide spectrum of disease, from asymptomatic to critical or terminal respiratory failure or multi-organ dysfunction. A new […]
Researchers from the University of Granada warn that an accumulation of fatty tissue in the neck (both the double chin and the deeper deposits, located between muscles and around the cervical vertebrae) is a predictor of central and overall adiposity, cardiometabolic risk, and a pro-inflammatory profile in sedentary young adults. A study conducted by researchers […]
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