Researchers discover balance between two protein counteracting forces in hereditary ataxias

Collaborating with the University of Oxford, Professor Ho Yin Edwin Chan’s research team from the School of Life Sciences of The Chinese University of Hong Kong (CUHK) recently unveiled the counteracting relationship between pre-mRNA-processing factor 19 (Prpf19) and exocyst complex component 7 (Exoc7) in controlling the degradation of disease protein and neurodegeneration of the rare […]

Why Nigeria must include parents in plans to protect girls from cervical cancer

Cervical cancer is the second most common cancer among women in Nigeria. There were 31,955 new cervical cancer cases in West Africa in 2018, and Nigeria accounted for almost half (14,943). There were also 10,403 deaths (28 deaths every day) from cervical cancer in the country in the same year. About 70% of all cervical […]

CAR T-cell therapy generates lasting remissions in patients with multiple myeloma

In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found. In a study posted online today by the New England Journal of Medicine, trial leaders report that almost 75% of the […]

AstraZeneca EU supply chain shortfall continues in second quarter

Pharmaceutical giant AstraZeneca said Tuesday its EU supply chains would only be able to deliver half of an expected supply of Covid-19 vaccines to the bloc in the second quarter—but that it would look to make up the shortfall from elsewhere. A spokesman for the British drugs group told AFP AstraZeneca was “working to increase […]

Woman contracts COVID-19 from lung transplant in a first

A lifesaving operation turned tragic when a Michigan woman contracted COVID-19 from her double lung transplant last year and died soon after. The case marks the first time that doctors have confirmed COVID-19 transmission through an organ transplant, according to a report of the case, published Feb. 10 in the American Journal of Transplantation. A […]

How stigma and discrimination link to rise in drug deaths among Scotland’s poor

For more than a decade, drug-related deaths (DRD) in Scotland have been rising – alongside evidence which suggests that the country has had much less success in treating and supporting people who use drugs compared to the rest of the UK and Europe. The figures for 2019, which were released in December 2020, recorded 1,264 […]

New research on mitochondrial function can play significant part in serious disease

Disorders of cellular energy supply can cause a number of serious diseases, but also seem to be connected to aging. More research is needed on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects their function in mice and fruit flies. […]