Men in Australia are more likely than women to be obese, yet they are underrepresented in weight loss trials. A study published in PLOS Medicine, by Eleanor Quested at Curtin University in Perth, Australia and colleagues found that participants in a men-only, sports-themed weight loss program increased physical activity and lost more weight than men […]
Organoids help bridge gap between laboratory study and animal modeling of colorectal cancer
Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have biofabricated human colorectal cancer miniature organs, called organoids, to better understand how a tumor grows in its natural microenvironment and its response to therapies. This new study is the first to replicate observations of native tumor tissue in a laboratory model and validate it […]
Can a high-tech headband really help you beat the heat?
Can a high-tech headband really help you beat the heat – or are these other products a cooler option to tackle this week’s heatwave? As much as we might welcome the hotter weather forecast for this weekend, sweltering, sticky days — and nights — can be a challenge. Alice Jaffe asked experts to assess some […]
Immune cell steroids help tumours suppress the immune system, offering new immunotherapy targets
A study has revealed that tumors can evade the immune system by telling immune cells to produce immunosuppressive steroids. Researchers from the Wellcome Sanger Institute, Department of Pathology, University of Cambridge, and MRC Cancer Unit, discovered that immune T cells from mouse skin and breast tumors secrete steroids, and that preventing this steroid production reduced […]
Militant optimism: A state of mind that can help us find hope in dark times
The COVID-19 crisis has had a grave impact on jobs, wellbeing, mental health and the economy worldwide. But it has also prompted public expressions of hope—people have come together to sing on balconies and clap in the streets. Communities have been joining forces, with a surge in people donating to local food banks and looking […]
Study says crowdsourced data could help map urban food deserts
New research from The University of Texas at Dallas suggests food deserts might be more prevalent in the U.S. than the numbers reported in government estimates. In a feasibility study published in the journal Frontiers in Public Health, scholars found that the methods used by the U.S. Department of Agriculture (USDA) to identify areas with […]
Oropharyngeal secretions may help reduce false negative COVID-19 test results
As the global battle to understand and eliminate the coronavirus continues, a new study published in the Journal of Dental Research demonstrates that testing of oropharyngeal secretions (OS) may reduce the number of false negative results from nasal swab testing of patients who have seemingly recovered from the disease. In the study, led by Jingzhi […]
People with delusions understand metaphor differently – here’s how it could help explain schizophrenia
Figurative language, by which the speaker intends to communicate something other than what is actually said by the words used, is commonplace in human communication. Some claim that metaphorical expressions such as “My home has become a prison” or “My daughter is a monster” are used on average six times during every minute of conversation. […]
New DNA sequencing technique may help unravel genetic diversity of cancer tumors
The ability to sequence the genome of a tumor has revolutionized cancer treatment over the last 15 years by identifying drivers of cancer at the molecular level. But understanding the genetic diversity of individual cells within a tumor and how that might impact the disease progression has remained a challenge, due to the current limitations […]
Vitamin D could help mitigate chemotherapy side effects
As many cancer patients will confirm, the chemotherapy prescribed to kill the disease is often more debilitating than the cancer itself, with a range of horrendous side effects. Gastrointestinal mucositis, a painful inflammation and ulceration of the digestive tract, is one adverse outcome of chemotherapy that has plagued cancer sufferers for years, and for which […]