Biden Administration to Invest $1.7 B to Fight COVID-19 Variants

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Biden administration plans to invest $1.7 billion to help the CDC and states fight COVID-19 variants in the U.S. through better detection and genomic sequencing efforts, the White House announced on Friday. The original strain of the coronavirus comprises about […]

US Seeks to Stop Illumina From Purchasing Cancer-Testing Firm Grail

WASHINGTON (Reuters) – The Federal Trade Commission will seek to stop Illumina Inc’s $7.1 billion proposed acquisition of cancer detection test maker Grail Inc, the agency said in a statement on Tuesday. The agency said the deal would slow innovation for tests that are designed to detect multiple kinds of cancer. Illumina, a life sciences […]

Nawal El Saadawi: A Life Lived Dangerously

Dr Nawal El Saadawi People around the world are mourning the death of Egypt’s Nawal El Saadawi, MD, the fiery Arab women’s rights advocate. She died March 21 in Cairo at age 89 after a long illness. Born October 27, 1931, the second of nine children, El Saadawi avoided a child marriage and went on […]

Genetic Testing for Breast and Ovarian Cancer

A large, retrospective study shows how germline genetic testing has evolved over time in women with breast or ovarian cancer and reveals a path forward for testing these patients. Investigators found racial and ethnic disparities in genetic testing as well as “persistent underuse” of testing in patients with ovarian cancer. The team also discovered that […]

First Oral SMA Treatment Gets EMA Panel Thumbs Up

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended marketing authorization for risdiplam (Evrysdi), the first treatment that can be given orally to patients with certain types of spinal muscular atrophy (SMA). Risdiplam is “expected to increase survival of motor neurons and reduce symptoms of the disease,” […]

22-Gene Classifier May Help Guide Decision Making After Radical Prostatectomy

NEW YORK (Reuters Health) – The Decipher genomic classifier (GC) is a promising tool to help determine which men will benefit from hormone therapy in addition to salvage radiation after radical prostatectomy, researchers say. “These findings are the first solid pieces of evidence to lead to a practice change,” Dr. Phuoc Tran of Johns Hopkins […]

Liquid vs Tissue Biopsy in Prostate Cancer: Why Not Both?

The genomic landscape of circulating tumor DNA (ctDNA) was comparable to the landscape of tissue biopsies in a large study of patients with metastatic castration-resistant prostate cancer (mCRPC), according to researchers. The type and frequency of genomic alterations observed were largely similar in ctDNA and tissue, and there was high concordance for BRCA1/2 alterations. Comprehensive […]