MONDAY, Oct. 5, 2020 — Two U.S. researchers and a British scientist have been awarded the 2020 Nobel Prize in physiology or medicine for major contributions to the fight against blood-borne hepatitis. Hepatitis C causes 400,000 deaths worldwide each year, The Washington Post reported. The three recipients are: Harvey Alter, a clinical scientist at a […]
Pfizer Receives FDA Fast Track Designation for Duchenne Muscular Dystrophy Investigational Gene Therapy PF-06939926
NEW YORK–(BUSINESS WIRE)–October 01, 2020 — Pfizer Inc. (NYSE: PFE) today announced that its investigational gene therapy candidate (PF-06939926) being developed to treat Duchenne muscular dystrophy (DMD) received Fast Track designation from the U.S. Food and Drug Administration (FDA). PF-06939926 is currently being evaluated to determine the safety and efficacy of this gene therapy in […]
FDA Approves Opdivo (nivolumab) + Yervoy (ipilimumab) as the First and Only Immunotherapy Treatment for Previously Untreated Unresectable Malignant Pleural Mesothelioma
PRINCETON, N.J.–(BUSINESS WIRE) October 2, 2020 — Bristol Myers Squibb (NYSE: BMY) today announced that Opdivo (nivolumab) 360 mg every three weeks plus Yervoy (ipilimumab) 1 mg/kg every six weeks (injections for intravenous use) was approved by the U.S. Food and Drug Administration (FDA) for the first-line treatment of adult patients with unresectable malignant pleural […]
Outcomes worse for deferred aortic valve replacement
(HealthDay)—For patients with symptomatic severe aortic stenosis, deferred aortic valve replacement (AVR) is associated with an increased risk for hospitalization for valve-related symptoms or worsening heart failure, according to a research letter published online Sept. 30 in JAMA Network Open. Christoph Ryffel, M.D., from the Bern University Hospital in Switzerland, and colleagues examined outcomes in […]
No room for abortions: unwanted pregnancies in virus-hit S.Africa
South African student Jessica* had already missed two periods when she shyly slipped into a clinic to seek an abortion in early July, as the coronavirus outbreak was reaching its peak. Nurses scurrying to accomodate a long line of patients with varying ailments told the 19-year-old that the clinic was “fully booked” and advised her […]
Molecules responsible for radio-resistant glioblastoma identified
Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer. Glioblastoma multiforme (GBM), is the most aggressive type of brain cancer. It is treated by radiation therapy combined with chemotherapy. However, even with treatment, the five-year survival rate for GBM is […]
Early MRI scans can predict motor development risks for preterm infants
As many as 70% of very premature infants (born earlier than 32 weeks gestation) show signs of white matter abnormalities at birth. But only some of those infants go on to develop cognitive, language, motor, or behavioral disorders as they grow. Now, scientists say a new software tool can employ MRI scan data to predict […]
Researchers develop more accurate surgery-risk predictor for patients with cirrhosis
Physicians and researchers at the Perelman School of Medicine at the University of Pennsylvania, the Corporal Michael J. Crescenz VA Medical Center, VA Connecticut Healthcare System, and Beth Israel Deaconess Medical Center created a new prediction model which, when compared to older and widely-used models, provided better estimated risk of mortality after surgery for patients […]
How zika virus degrades an essential protein for neurological development, getting it to ‘eat itself’
In a study published in Autophagy, researchers at the University of Maryland (UMD) shed new light on how Zika virus hijacks our own cellular machinery to break down a protein that is essential for neurological development and cellular communication, getting it to “eat itself”. By triggering this process known as autophagy, Zika virus is able […]
WHO, partners roll out faster COVID tests for poorer nations
The World Health Organization announced Monday that it and leading partners have agreed to a plan to roll out 120 million rapid-diagnostic tests for the coronavirus to help lower- and middle-income countries make up ground in a testing gap with richer countries—even if it’s not fully funded yet. At $5 apiece, the antigen-based rapid diagnostic […]