Skoltech researchers and their colleagues from Russia, Germany, and the U.S. have found Prozac to reduce lipid concentrations in juvenile macaques who received the antidepressant for two years, compared to a control group of untreated animals. While none of the monkeys in the study were depressed, the findings still offer a plausible biochemical explanation for […]
A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests. The finding, published online in Cell Metabolism, could help explain the “obesity paradox,” a phenomenon in which obese individuals have better short- and medium-term cardiovascular disease prognoses compared with those who […]
A collection of genetic variants influences the expression of obesity-associated genes in both the brain and fat tissue, according to a new study from researchers at the University of Chicago. The research team found that changes in the expression of the obesity-associated genes correlated with both metabolic and behavioral changes, suggesting that these variants produce […]
In adults with obesity or overweight, weekly treatment with the glucagon-like peptide 1 (GLP1) receptor agonist semaglutide leads to reduced excess body fat and increased lean body mass, according to an industry-sponsored study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting. “Our findings suggest that semaglutide, through body weight loss and improvement of […]
Consumption of a high fat diet may be activating a response in the heart that is causing destructive growth and lead to greater risk of heart attacks, according to new research. In a paper published in Biochemical and Biophysical Research Communications, researchers looked at the effect of feeding mice a high fat diet on oxidative […]
When Caroline Watson suddenly gained weight and grew to 5ft 8in tall at the age of nine, her concerned mum took her to the GP. But the issue was dismissed as ‘puppy fat’ and doctors advised the child to just ‘stop eating potatoes’. The truth was that her sudden growth spurt was due to a […]
There’s fat all over your body, not just between your ribcage and your waistband. The adipose tissue that resides under your skin is a connective tissue called subcutaneous fat, and it sort of jiggles when you flick it or pinch it. But there’s another kind of fat that’s harder to spot unless you happen to […]
Sugars and fats are the primary fuels that power every cell, tissue and organ. For most cells, sugar is the energy source of choice, but when nutrients are scarce, such as during starvation or extreme exertion, cells will switch to breaking down fats instead. The mechanisms for how cells rewire their metabolism in response to […]
Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat and muscle cells. But it’s their ability to stimulate the repair of damaged tissue that has captured the interest of researchers worldwide, with MSCs demonstrating therapeutic effects in the treatment of conditions such as heart disease, […]
How much saturated fat is safe? Saturated fats are found in many foods, are generally regarded but as unhealthy. You increase the fat levels in the blood and the “bad” LDL cholesterol, increasing the risk of heart disease increases. However, such fats are generally always harmful, or there is also a safe for consumption? A […]
