Can an immunosuppressive cancer drug promote SARS-CoV-2 entry into host cells?

A new study, released on the bioRxiv* preprint server, shows that rapamycin, an immunosuppressive drug used in some cancers, and its analogs, may have an undesirable effect on viral entry into the host cells. This finding could inform their use to treat symptomatic coronavirus disease 2019 (COVID-19). There is a serious lack of effective antivirals […]

P681 mutation has little impact on transmissibility in the SARS-CoV-2 UK variant, finds study

The rollout of vaccines is on in an attempt to achieve population immunity against the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the recent emergence of several variants that have altered transmissibility, infectivity and virulence characteristics has cast doubt on the feasibility of this goal. A […]

CAL20.C SARS-CoV-2 variant skyrocketing in California evades host immune response

The effect of different neutralizing antibodies, both vaccine-elicited and from convalescent sera, suggests new variants are emerging that can evade the human immune response. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to host cells via its spike protein, which has two parts, the S1 and S2 subunits. The S1 subunit has the receptor-binding […]

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients. The discovery points the way to a search for novel treatments for the disease as well as […]

Elelyso

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. ELELYSO® taliglucerase alfa rpc Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about Elelyso. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All […]

Imatinib Apotex

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. IMATINIB APOTEX CMI V1 Contains the active ingredient imatinib mesilate Consumer Medicine Information What is in this leaflet Read this leaflet carefully before taking your medicine. This leaflet answers some of the common questions about imatinib. It does not contain all the […]

Onivyde

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. ONIVYDE Nanoliposomal irinotecan – Irinotecan 4.3 mg/mL concentrate for solution for infusion Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about ONIVYDE. It does not contain all of the available information. All medicines have risks and […]

Tryzan

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. TRYZAN CAPS & TRYZAN TABS ramipril CONSUMER MEDICINE INFORMATION What is in this leaflet This leaflet answers some common questions about TRYZAN. It does not contain all the available information. It does not take the place of talking to your doctor or […]

Sporanox Capsules

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. SPORANOX® CAPSULES Itraconazole Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about SPORANOX capsules. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All […]