Study shows potential of heartburn drug for COVID-19 According to an observational study, which was conducted at Irving, Medical Center of Columbia University (USA), could help a common drug for heartburn by the Coronavirus SARS-CoV-2-induced disease COVID-19. In a new study has shown that COVID-19-patients and in -patients in the Famotidine, a common drug for […]
Screening for drug use can be reasonable, but not evidence-based
Little evidence supports the new recommendations for clinical screening for drug use. Do the potential benefits outweigh the potential harms? In the June 9 issue of JAMA, the U.S. Preventive Services Task Force (USPSTF) recommends that clinicians screen for unhealthy drug use (that is, any use of drugs that are illegal or medications not used […]
Researchers find potential drug treatment targets for alcohol-related liver disease
Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant. But now, a team led by researchers from Massachusetts General Hospital (MGH) has uncovered key molecular step stones in ALD that may provide targets for drug therapy development. Their work was recently published in […]
The osteoporosis wonder drug that helps rebuild crumbling bones
The osteoporosis wonder drug that helps rebuild crumbling bones and could save 500,000 people a year a visit to the fracture clinic More than three million Britons suffer from the brittle bone disease osteoporosis Some 500,000 osteoporosis sufferers are treated in hospital a year for fractures The condition often goes undetected until a sufferer starts […]
Laws that punish pregnant drug abusers aren’t working, new study finds
A new study co-authored by a University of Central Florida researcher shows that laws that punish substance use during pregnancy actually do more harm than good. These unintended consequences include keeping women from getting the treatment they need and failing to reduce the number of babies addicted to drugs. The study, which was published Monday […]
FDA warns of heart risks with Trump-promoted malaria drug
The U.S. Food and Drug Administration on Friday warned doctors against prescribing a malaria drug touted by President Donald Trump for treating the new coronavirus except in hospitals and research studies. In an alert, regulators flagged reports of sometimes fatal heart side effects among coronavirus patients taking hydroxychloroquine or the related drug chloroquine. The decades-old […]
Study identifies potential drug treatments for telomere diseases
Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely. Using cells donated by patients with the disease, researchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center identified several small molecules that appear to reverse this cellular aging process. […]
Possible coronavirus drug identified by Australian scientists
A collaborative study led by Monash University’s Biomedicine Discovery Institute (BDI) in Melbourne, Australia, with the Peter Doherty Institute of Infection and Immunity (Doherty Institute), has shown that an anti-parasitic drug already available around the world kills the virus within 48 hours. The Monash Biomedicine Discovery Institute’s Dr. Kylie Wagstaff, who led the study, said […]
Tailoring an anti-cancer drug for optimal tumor cell killing
In a study published this week in Science, Université de Montreal researchers report key structural and biochemical differences among a class of anti-cancer drugs known as PARP inhibitors. These distinguishing differences were linked to differing capacities of PARP inhibitors to kill cancer cells. The research resolves a long-standing and perplexing quandary over differences between the […]
New drug could reverse treatment resistance in advanced multiple myeloma
Researchers at the VU University Medical Center in the Netherlands have tested a new drug in patient samples and mice with multiple myeloma and discovered that it was effective even in advanced disease—a point when many patients currently run out of options. These promising results could pave the way for the new drug to be […]