Congress passes immunosuppressive drug coverage expansion for kidney transplant patients

The US Senate passed the Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act as part of a broad year-end legislative package, extending Medicare coverage of life saving immunosuppressive medications for the life of the kidney transplant. An estimated 375 adult kidney transplant recipients lose their transplant every year due to a lack of coverage […]

Novel combination therapy may help overcome mTOR drug resistance in AML

Soon after rapamycin, the first mTOR inhibitor, emerged in 1990s as a potential treatment against unwanted cell proliferation, many cancer experts had hoped emerging drugs targeting mTOR would become a breakthrough targeted therapy for children and adults suffering relapses of acute myeloid leukemia (AML) and other cancers where mTOR activity is abnormally high. However, numerous […]

Drug may boost vaccine responses in older adults

A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in eLife shows. The results may lead to new approaches to protect older individuals from viruses such as the one causing the current COVID-19 pandemic and influenza. “Older adults […]

Researchers target thyroid cancer with triple threat drug combination

Combining a gene-targeted drug, a cancer-bursting virus and a drug that removes the immune system’s brake pedal can tackle thyroid cancer with newfound gusto, research has found. The triple-threat combination attacks cancer’s ability to develop resistance to a single drug by launching a multi-pronged attack, backing it into a corner with strong results in mice. […]

Researchers identify promising drug combination for melanoma

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer. Lead author Amanda Truong, trainee in the McMahon Lab at HCI and student at the U of U, explains uveal melanoma patients frequently have changes in […]

FDA panel urges rejection of experimental Alzheimer’s drug

Government health advisers sharply criticized a closely watched Alzheimer’s drug on Friday, concluding there wasn’t enough evidence that the experimental drug slowed the brain-destroying disease. The panel of outside experts for the Food and Drug Administration agreed that a pivotal study in patients failed to show “strong evidence” that the drug worked. The experts warned […]

An age of anxiety and drug use in COVID-19

UNSW’s Dr. George Dertadian says the anxieties, stresses and strains people are dealing with in the pandemic could be influencing the use of drugs in society. “The combination of these existential threats and personal problems have the potential to drive up the use of non-medical pharmaceuticals,” says Dr. Dertadian, a social researcher who has published […]

Pregnant women with severe nausea and vomiting find relief with seizure drug

A rare, debilitating condition in pregnancy that causes nausea and vomiting so severe that some women end up terminating their pregnancies can be effectively treated with the seizure drug gabapentin. That is the finding of a new study of 21 women with the condition led by the University at Buffalo and published on Oct. 29 […]