A Griffith University-led research team has discovered how a therapeutic target common among debilitating neurodegenerative disorders is activated, which could help accelerate drug development. In a study published in the journal Neuron, the researchers from Griffith University’s Institute for Glycomics, the University of Queensland and Washington University, analyzed the structure and function of a protein […]
How stigma and discrimination link to rise in drug deaths among Scotland’s poor
For more than a decade, drug-related deaths (DRD) in Scotland have been rising – alongside evidence which suggests that the country has had much less success in treating and supporting people who use drugs compared to the rest of the UK and Europe. The figures for 2019, which were released in December 2020, recorded 1,264 […]
Immunotherapy—targeted drug combination improves survival in advanced kidney cancer
Patients with advanced kidney cancer, who received a targeted drug combined with a checkpoint-blocker immunotherapy agent had longer survival than patients treated with the standard targeted drug, said an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial. The survival benefit demonstrates that an immune checkpoint inhibitor together with a targeted […]
Drug is promising against pancreatic and breast cancers
ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also […]
The Importance of Pharmaceutical Packaging in Different Applications
Drugs may be distributed in a variety of primary (innermost, touching the drug) and secondary (outermost, visible to the user) pharmaceutical packaging, depending on the requirements of the drug itself and the intended end-user. Pharmaceutical Packaging. Image Credit: Mr.1/Shutterstock.com Drugs may be in the liquid, solid, or gas phase, and packaging must accommodate the specific […]
COVID patients treated with hepatitis drug cleared infection quickly
Coronavirus patients treated with a experimental hepatitis drug were FOUR times more likely to have cleared the infection within seven days, study finds Peginterferon-lambda is a man-made form of a naturally occurring protein that calls for immune cells to attack a virus and is mainly used to treat hepatitis Receptors for the drug are found […]
Prostate drug associated with lower risk of Parkinson’s disease
Taking a particular type of medication to treat enlarged prostate is associated with a reduced risk of developing Parkinson’s disease, according to a large observational study led by researchers at the University of Iowa, with colleagues in Denmark and China. The findings, published Feb. 1 in JAMA Neurology, provide compelling evidence that terazosin, and similar […]
U.S. Food and Drug Administration Approves Opdivo (nivolumab) in Combination with Cabometyx (cabozantinib) as First-line Treatment for Patients with Advanced Renal Cell Carcinoma
PRINCETON, N.J.–(BUSINESS WIRE) January 22, 2021– Bristol Myers Squibb (NYSE: BMY) today announced that Opdivo (nivolumab) 240 mg (injection for intravenous use) every two weeks or 480 mg every four weeks in combination with Cabometyx (cabozantinib) 40 mg once daily tablets was approved by the U.S. Food and Drug Administration (FDA) for the first-line treatment […]
FDA approves 1st long-acting HIV drug combo, monthly shots
Doctors may have cured second man of HIV Doctors in London performed a bone marrow transplant on the patient and are calling the results ‘long-term remission’; Steve Harrigan reports. U.S. regulators have approved the first long-acting drug combo for HIV, monthly shots that can replace the daily pills now used to control infection with the […]
New drug form may help treat osteoporosis, calcium-related disorders
A novel form of a drug used to treat osteoporosis that comes with the potential for fewer side effects may provide a new option for patients. The work is supported by the National Institutes of Health and is published in Biophysical Journal. Purdue University innovators developed a stabilized form of human calcitonin, which is a […]