A repurposed arthritis drug has shown positive results in a clinical trial of patients hospitalized with COVID-19, according to a paper published Wednesday in the New England Journal of Medicine. Tofacitinib, taken orally and sold under the brand name Xeljanz among others, was tested in a trial of 289 patients hospitalized with severe COVID across […]
Targeted drug found effective in thwarting pancreatic tumors
Pancreatic cancer is an aggressive disease in which malignant cells form in the tissues of the pancreas, a long and flat gland located behind the stomach that helps with digestion and blood sugar regulation. Because pancreatic cancer is difficult to detect early, it is associated with a low survival rate, accounting for just over 3% […]
New and improved drug to counter spinal anesthesia blues during C-sections
Today, deliveries via cesarean sections (or c-sections) have become quite common globally. Sometimes, c-sections are a medical necessity when normal deliveries become risky either for the mother or the baby. At other times, it can be a choice. C-sections today have become considerably safer procedures than they were a few decades ago, but there is […]
New drug is gamechanger in psoriasis treatment
A novel drug almost entirely cleared moderate to severe psoriasis in over 60% of the patients who took part in two phase three clinical trials of a new drug. The University of Manchester and Salford Royal NHS Foundation Trust led studies on Bimekizumab , both published in the prestigious New England Journal of Medicine today, […]
Novartis, Roche team up on COVID pneumonia drug
Novartis announced Thursday it will join forces with fellow Swiss pharmaceutical giant Roche to produce tocilizumab, a drug being tested for its effectiveness against COVID-19-linked pneumonia. It is the third time Novartis has made its production capacities available to a competitor during the coronavirus pandemic, as several laboratories strike unprecedented partnerships to fight the global […]
Study suggests common drug could be used to prevent certain skin cancers
New data published by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) suggests that an oral drug currently used in the clinical setting to treat neuromuscular diseases could also help prevent a common form of skin cancer caused by damage from ultraviolet-B (UVB) […]
Biologists create better method to culture cells for testing drug toxicity
When a new drug is being developed, the first question is, “Does it work?” The second question is, “Does it do harm?” No matter how effective a therapy is, if it harms the patient in the process, it has little value. Doctoral student Robert Skolik and Associate Professor Michael Menze, Ph.D., in the Department of […]
New drug candidate against COVID-19
SARS-CoV-2, the virus responsible for the COVID-19 pandemic, arrived one year ago and turned our lives upside-down. While worldwide vaccination programs are currently ongoing, we do not yet know for how long the vaccine will provide immune protection against infection, and if the currently approved vaccines can provide protection against the emerging virus variants. In […]
On the hunt for a dengue antiviral: Scientists comb through scores of compounds to find a drug for ‘breakbone fever’
The ‘dengue belt’ stretches around much of the planet crossing continents, cultures and time zones, a vast region linked by a common fate: a mosquito-borne disease that can be prevented for a select number of people with a somewhat quirky vaccine. Dengue, however, remains a source of misery for many, a viral infection without an […]
Piece work increases drug use among Americans
Researchers have looked at whether workers who are paid by the piece have a greater risk of using alcohol and hard drugs than employees on fixed pay. “It’s not difficult to argue that piece work and performance pay can increase productivity and benefit both employees and employers, but they have a price,” says Colin Green, […]