Ears: Facts, Function & Disease

The ear isn’t just the hearing organ. It is a complex system of parts that not only allows humans to hear, but also makes it possible for humans to walk.  How big are human ears? Ears come in many shapes and sizes. Typically, men’s ears are larger than women’s, according to a study in the […]

Huntington’s disease driven by slowed protein-building machinery in cells

In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington’s disease, raising high hopes for a quick cure. Yet today, there’s still no approved treatment. One difficulty has been a limited understanding of how the mutant huntingtin protein sets off brain cell death, says neuroscientist Srinivasa Subramaniam, Ph.D., of Scripps Research, Florida. In […]

High fat diets may over-activate destructive heart disease protein

Consumption of a high fat diet may be activating a response in the heart that is causing destructive growth and lead to greater risk of heart attacks, according to new research. In a paper published in Biochemical and Biophysical Research Communications, researchers looked at the effect of feeding mice a high fat diet on oxidative […]

New research on mitochondrial function can play significant part in serious disease

Disorders of cellular energy supply can cause a number of serious diseases, but also seem to be connected to aging. More research is needed on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects their function in mice and fruit flies. […]

First-in-human clinical trial to assess gene therapy for Alzheimer’s disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia. The […]

CPAP treatment increases physical activity in adults with sleep apnea, heart disease

A new study found that treating obstructive sleep apnea with CPAP therapy increased self-reported physical activity in adults with a history of heart disease. During a mean follow-up period of 3.7 years, the group treated with CPAP therapy reported approximately 20% higher levels of moderate physical activity compared with the control group. The study also […]

Scientists switch on tissue repair in inflammatory bowel disease

A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University. This opens the way for more effective treatment of inflammatory bowel disease, including ulcerative colitis and Crohn’s disease. The study was carried out on humans and mice. When […]

Winner-takes-all synthetic gene circuit process opens new pathways to disease treatment

A new process for inserting synthetic gene circuits into host cells, developed by a team of bioengineers at Arizona State University, has broad implications for improving the effectiveness of a range of disease therapies. Synthetic biology is an interdisciplinary research field that uses engineering principles to create biological components that don’t exist in the natural […]