Chemotherapy attacks all cells in our body and not just cancer cells, which is why patients undergoing the treatment often experience side effects such as physical weakness, hair loss and nausea. However, because cancer cells divide and spread faster than most normal cells, cancer cells are more sensitive to chemotherapy, which kills cells by inhibiting […]
Scientists discover a key genetic driver of lymphomas
Mutations in proteins called histone H1, which help package DNA in chromosomes, are a frequent cause of lymphomas, according to a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and The Rockefeller University. The findings could lead to new approaches to treating these cancers. Scientists in recent years have observed that mutations in histone […]
Genome archeologists discover path to activate immune response against cancer
Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection. The work builds on Princess Margaret Senior Scientist Dr. De Carvalho’s previous ground-breaking discovery known as viral mimicry— the ability to cause cancer cells to behave as though they have been infected, thereby […]
Researchers discover the microbiome’s role in attacking cancerous tumours
Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine (CSM) have discovered which gut bacteria help our immune system battle cancerous tumors and how they do it. The discovery may provide a new understanding of why immunotherapy, a treatment for cancer that helps amplify the body’s immune response, works in […]
Scientists discover key element of strong antibody response to COVID-19
A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19. The scientists, whose study appears July 13 in Science, reviewed data on nearly 300 anti-SARS-CoV-2 antibodies that their labs and others have found in convalescent COVID-19 […]
Researchers discover key player in hepatitis A virus infection
How hepatitis A virus (HAV) manages to enter liver cells called hepatocytes and initiate infection had remained a mystery for fifty years until now. University of North Carolina School of Medicine researchers designed experiments using gene-editing tools to discover how molecules called gangliosides serve as de facto gatekeepers to allow the virus entry into liver […]
Coronavirus 'slathers the insides of lungs in slime' experts discover
Doctor describes how coronavirus ‘covers the insides of lungs in slime’ that suffocates the respiratory air sacs Researchers performed two autopsies on coronavirus patients, including a 77-year-old man from Oklahoma The examination revealed a thick coating inside his lungs that resembled slime or paint It caused airway inflammation and damage to the alveoli – the […]