Brain Rhythm Predicts Response to DBS for Severe Depression

Brain beta rhythm predicts early and robust response to deep brain stimulation (DBS) for severe depression in new findings that could help optimize and personalize DBS treatment protocols, early research suggests. In a small study, investigators found brief stimulation at the time of implantation of DBS leads induced a rapid and consistent decrease in beta […]

Lower Thyroid Hormone Levels a Red Flag for Elevated Suicide Risk?

Patients with comorbid anxiety and mood disorders who have reduced, albeit “normal,” serum levels of thyroid-stimulating hormone (TSH) may be at increased risk for suicidal ideation, new research suggests. In a cross-sectional study, clinical data on diagnosis, medication use, and symptom scores were gathered, along with assessments of blood levels of thyroid axis hormones, in […]

Adolescent Depression: When to Intervene and With Whom

NEW YORK (Reuters Health) – New data from a long-running study shed light on trajectories of depressive symptoms experienced from adolescence to early adulthood, which could help pinpoint when to intervene in adolescent depression, and with whom. “Depression often first emerges in adolescence and, for many, is a lifelong disorder. The long-term clinical course of […]

Drinking coffee 'helps to improve mood' as days get shorter

The clocks are going back this weekend – which means we are headed for shorter and darker days. Those who suffer from Seasonal Affective Disorder (SAD) will know just how much of a detrimental impact the lack of light and warmth can have on your mental state, but there are things you can do to […]

Relapse Risk Increased With Antidepressant Discontinuation

For primary care patients feeling well enough to discontinue antidepressant medication, there was a higher rate of depressive relapse among those who discontinued therapy, compared with those who did not, a new study shows. The results of the Antidepressants to Prevent Relapse in Depression (ANTLER) trial also suggest that “many patients can discontinue their antidepressants safely […]

Pandemic-Related Stressors Identified in Parkinson’s Disease

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Social distancing and the shutdown of services like physical and occupational therapy because of COVID-19 have had a profound impact on the mental health of people with Parkinson’s disease, a team of researchers in the Netherlands reported, but they also identified […]

Depression during menopause: How to spot it and treat it

(HealthDay)—Emotional changes in the run-up to menopause can sometimes lead to depression. It can be important to see a doctor to help determine whether you’re just feeling stressed or “blue”—or whether you might have clinical or major depression, a condition associated with a chemical imbalance in the brain. Changing hormones during perimenopause—the time when a […]

Can anxiety and depression actually cause memory loss? We asked an expert to explain

Ever wondered why your memory gets hazy when you’re struggling with anxiety or depression? Read this. There’s nothing quite like a random viral tweet to get you rethinking everything you thought you knew, right? Last week, during an innocent morning scroll, such a tweet popped up on my timeline – and I’ve been thinking about […]

Internet CBT for depression reviewed and analyzed

Internet-based cognitive behavioral therapy (CBT) for depression is often just as effective as traditional CBT. This is clear from an international study involving scientists at the University of Gothenburg. However, some online treatments have components that can be harmful. Internet CBT (iCBT) as a method of delivering treatment is on the increase. Nevertheless, it has […]

Low-Dose Nitrous Oxide Shows Benefit for Resistant Depression

A 1-hour treatment with a low concentration of nitrous oxide, commonly known as “laughing gas,” appears to relieve symptoms of treatment-resistant major depression (TRMD), with effects lasting as long as several weeks, new research suggests. In a trial with a crossover design, investigators randomly assigned 28 patients with severe TRMD to receive a single 1-hour […]