Immune cells in cerebrospinal fluid predict response to immunotherapy

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies. Immune checkpoint inhibitors including anti-PD1, anti-PD-L1, and […]

New device decreases accidental cerebrospinal fluid leaks during epidural anaesthesia

Epidural anesthesia is a technique that requires great accuracy to avoid accidentally puncturing the dura mater, one of the three meninx that protect the central nervous system. The cerebrospinal fluid, which feeds the nervous system, is located under the dura mater. Leaks of this fluid can cause strong headaches that can be crippling and delay […]